Blastulation rates decline in a linear fashion from euploid to aneuploid embryos with single versus multiple chromosomal errors.

Vega, Mario; Breborowicz, Andrzej; Moshier, Erin L.; McGovern, Peter G.; Keltz, Martin D

doi:10.1016/j.fertnstert.2014.04.026

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Blastulation rates decline in a linear fashion from euploid to aneuploid embryos with single versus multiple chromosomal errors.

Author(s): Mario Vega ¹ , Andrzej Breborowicz ² , Erin L Moshier ³ , Peter G McGovern ² , Martin D Keltz ²

Publication date (Electronic): Aug 2014

Journal: Fertility and sterility

Keywords: Aneuploidy, PGS, assisted reproduction, embryo quality, preimplantation genetic screening

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Abstract

To test the hypothesis that the blastulation rate is higher in euploid embryos than in aneuploid embryos as assessed by cleavage-stage biopsy with array-comprehensive genomic hybridization (aCGH).

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Journal ID (iso-abbrev): Fertil. Steril.

Title: Fertility and sterility

ISSN (Electronic): 1556-5653

ISSN (Print): 0015-0282

Publication date (Electronic): Aug 2014

Volume: 102

Issue: 2

Affiliations

[1 ] Department of Obstetrics and Gynecology, Mount Sinai St. Luke's-Roosevelt, Icahn School of Medicine at Mount Sinai, New York. Electronic address: mgvega@chpnet.org.

[2 ] Department of Obstetrics and Gynecology, Mount Sinai St. Luke's-Roosevelt, Icahn School of Medicine at Mount Sinai, New York.

[3 ] Department of Community and Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

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Publisher Item ID: S0015-0282(14)00386-0

DOI: 10.1016/j.fertnstert.2014.04.026

PubMed ID: 24890269

SO-VID: efdeb3fc-84a1-46be-bd25-989240005b61

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Keywords: Aneuploidy,PGS,assisted reproduction,embryo quality,preimplantation genetic screening

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Keywords: Aneuploidy, PGS, assisted reproduction, embryo quality, preimplantation genetic screening

Blastulation rates decline in a linear fashion from euploid to aneuploid embryos with single versus multiple chromosomal errors.

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