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      Lifestyle chemistries from phones for individual profiling

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          Significance

          This paper introduces the concept of skin-associated lifestyle chemistries found on personal belongings as a form of trace evidence. We propose a mass spectrometry-based approach to illuminate chemical traces recovered from personal objects. Using a chemical composite recovered from a swab of a phone, as a representative personal belonging, we can provide insights into personal lifestyle profile by predicting the kind of beauty product the individual uses, the food he/she eats, the medications he/she takes, or the places he/she has been. Therefore, the chemical interpretation of traces recovered from objects found on a crime scene can help a criminal investigator to learn about the lifestyle of the individual who used or touched these objects.

          Abstract

          Imagine a scenario where personal belongings such as pens, keys, phones, or handbags are found at an investigative site. It is often valuable to the investigative team that is trying to trace back the belongings to an individual to understand their personal habits, even when DNA evidence is also available. Here, we develop an approach to translate chemistries recovered from personal objects such as phones into a lifestyle sketch of the owner, using mass spectrometry and informatics approaches. Our results show that phones’ chemistries reflect a personalized lifestyle profile. The collective repertoire of molecules found on these objects provides a sketch of the lifestyle of an individual by highlighting the type of hygiene/beauty products the person uses, diet, medical status, and even the location where this person may have been. These findings introduce an additional form of trace evidence from skin-associated lifestyle chemicals found on personal belongings. Such information could help a criminal investigator narrowing down the owner of an object found at a crime scene, such as a suspect or missing person.

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          Author and article information

          Journal
          Proc Natl Acad Sci U S A
          Proc. Natl. Acad. Sci. U.S.A
          pnas
          pnas
          PNAS
          Proceedings of the National Academy of Sciences of the United States of America
          National Academy of Sciences
          0027-8424
          1091-6490
          29 November 2016
          14 November 2016
          14 November 2016
          : 113
          : 48
          : E7645-E7654
          Affiliations
          [1] aCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego , La Jolla, CA 92037;
          [2] bDepartment of Pediatrics, University of California, San Diego , La Jolla, CA 92037;
          [3] cDepartment of Computer Science and Engineering, University of California, San Diego , La Jolla, CA 92093;
          [4] d Structural and Computational Biology Unit, European Molecular Biology Laboratory , 69117 Heidelberg, Germany;
          [5] e SCiLS GmbH , 28359 Bremen, Germany;
          [6] fCenter for Microbiome Innovation, University of California, San Diego , La Jolla, CA 92307;
          [7] gDepartment of Pharmacology, University of California, San Diego , La Jolla,CA 92037
          Author notes
          1To whom correspondence may be addressed. Email: pdorrestein@ 123456ucsd.edu or abouslimani@ 123456ucsd.edu .

          Edited by Jerrold Meinwald, Cornell University, Ithaca, NY, and approved October 5, 2016 (received for review June 21, 2016)

          Author contributions: A.B. and P.C.D. designed research; A.B. and A.V.M. performed research; M.W., N.B., and T.A. contributed analytic tools; A.B., A.V.M., Z.X., A.A., R.R.d.S., R.K., and P.C.D. analyzed data; and A.B., R.K., and P.C.D. wrote the paper.

          Article
          PMC5137711 PMC5137711 5137711 201610019
          10.1073/pnas.1610019113
          5137711
          27849584
          61571997-3345-48d3-a350-c14f6df3182a

          Freely available online through the PNAS open access option.

          History
          Page count
          Pages: 10
          Funding
          Funded by: DOJ | National Institute of Justice (NIJ) 100005289
          Award ID: 2015-DN-BX-K047
          Funded by: DH | National Institute for Health Research (NIHR) 501100000272
          Award ID: GMS10RR029121
          Categories
          PNAS Plus
          Physical Sciences
          Chemistry
          PNAS Plus

          trace evidence,skin,phones,lifestyle chemistries
          trace evidence, skin, phones, lifestyle chemistries

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