Microbiological Profile in Periodontitis and Peri-Implantitis: A Systematic Review.

Abstract

Understanding the microbiological makeup of peri-implant biofilm could contribute to the discovery of focused treatment strategies, improving the outcome of peri-implantitis management. However, the bacterial profile in diseased periodontal and peri-implant sulci is still unclear. This systematic review aims to analyze the microbiological similarities and differences between diseased periodontal and peri-implant sulci based on the available literature evidence. A thorough search was conducted in electronic databases such as PubMed, Google Scholar, and Cochrane, as well as a manual search employing the eligibility criteria. After a thorough review, studies evaluating the microbial composition acquired from plaque samples obtained from patients with diseased periodontal and peri-implant sulci were chosen. The selected 8 studies evaluated the differences in microbial profile in periodontitis and peri-implantitis. Five studies found a statistically significant variation in the microbial profile between diseased periodontal and peri-implant sulci, while in one study, no changes in the microbiology of inflammatory peri-implant and periodontal sites were observed. In one of the two in situ studies, the structure of the transcription level and core species was different in peri-implantitis, whereas the other in situ study found that the 16S rRNA-based bacterial profile of both the diseases were different, while the functional genes, taxonomic, and virulence factor mRNA profiles were identical. According to existing studies, significant differences in the biofilm composition of diseased periodontal and peri-implant sulci were observed. Therefore, periodontitis and peri-implantitis have diverse microbial characteristics.