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      Multi‐disciplinary diabetic limb salvage programme in octogenarians with diabetic foot ulcers is not futile: An observational study with historical controls

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          Abstract

          This study evaluated the effectiveness of a multi‐disciplinary diabetic limb salvage programme in improving clinical outcomes and optimising healthcare utilisation in 406 patients aged ≥80 years with diabetic foot ulcers (DFUs), compared to 2392 younger patients enrolled from June 2020 to June 2021 and against 1716 historical controls using one‐to‐one propensity score matching. Results showed that elderly programme patients had lower odds of amputation‐free survival (odds ratio: 0.64, 95% CI: 0.47, 0.88) and shorter cumulative length of stay (LOS) compared to younger programme patients (incidence rate ratio: 0.45, 95% CI: 0.29, 0.69). Compared to the matched controls, participating in the programme was associated with 5% higher probability of minor lower extremity amputation, reduced inpatient admissions and emergency visits, shorter LOS but increased specialist and primary care visits (all p‐values <0.05). The findings suggest that the programme yielded favourable impacts on the clinical outcomes of patients aged≥80 years with DFUs. Further research is needed to develop specific interventions tailoring to the needs of the elderly population and to determine their effectiveness on patient outcomes while accounting for potential confounding factors.

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          WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition

          To provide global estimates of diabetes prevalence for 2019 and projections for 2030 and 2045.
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            Statistical Methods for Rates and Proportions

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              Practical Guidelines on the prevention and management of diabetic foot disease (IWGDF 2019 update)

              Diabetic foot disease results in a major global burden for patients and the health care system. The International Working Group on the Diabetic Foot (IWGDF) has been producing evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. In 2019, all IWGDF Guidelines have been updated based on systematic reviews of the literature and formulation of recommendations by multidisciplinary experts from all over the world. In this document, the IWGDF Practical Guidelines, we describe the basic principles of prevention, classification, and treatment of diabetic foot disease, based on the six IWGDF Guideline chapters. We also describe the organizational levels to successfully prevent and treat diabetic foot disease according to these principles and provide addenda to assist with foot screening. The information in these practical guidelines is aimed at the global community of health care professionals who are involved in the care of persons with diabetes. Many studies around the world support our belief that implementing these prevention and management principles is associated with a decrease in the frequency of diabetes-related lower extremity amputations. We hope that these updated practical guidelines continue to serve as reference document to aid health care providers in reducing the global burden of diabetic foot disease.
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                Author and article information

                Contributors
                lixia_ge@nhg.com.sg
                Journal
                Int Wound J
                Int Wound J
                10.1111/(ISSN)1742-481X
                IWJ
                International Wound Journal
                Blackwell Publishing Ltd (Oxford, UK )
                1742-4801
                1742-481X
                01 March 2024
                March 2024
                : 21
                : 3 ( doiID: 10.1111/iwj.v21.3 )
                : e14801
                Affiliations
                [ 1 ] Health Services and Outcomes Research National Healthcare Group Singapore Singapore
                [ 2 ] Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore
                [ 3 ] Section of Vascular Surgery, Department of Surgery and Cancer Imperial College London London UK
                [ 4 ] Medical Department National Healthcare Group Polyclinics Singapore Singapore
                [ 5 ] Department of Endocrinology Tan Tock Seng Hospital Singapore Singapore
                [ 6 ] Department of General Surgery Tan Tock Seng Hospital Singapore Singapore
                [ 7 ] Department of Endocrinology Khoo Teck Puat Hospital Singapore Singapore
                [ 8 ] Department of Orthopaedics Surgery Khoo Teck Puat Hospital Singapore Singapore
                [ 9 ] Vascular Surgery Service, Department of General Surgery Khoo Teck Puat Hospital Singapore Singapore
                [ 10 ] Department of Endocrinology Woodlands Health Singapore Singapore
                [ 11 ] Vascular Surgery Service, Department of Surgery Woodlands Health Singapore Singapore
                [ 12 ] Lee Kong Chian School of Medicine Nanyang Technological University Singapore Singapore
                Author notes
                [*] [* ] Correspondence

                Lixia Ge, Department of Health Services and Outcomes Research, National Healthcare Group Pte Ltd. 3 Fusionopolis Link 138 543, Singapore, Singapore.

                Email: lixia_ge@ 123456nhg.com.sg

                Author information
                https://orcid.org/0000-0001-8080-7020
                https://orcid.org/0000-0002-0956-5759
                https://orcid.org/0000-0002-4741-6754
                https://orcid.org/0000-0003-2289-5266
                Article
                IWJ14801
                10.1111/iwj.14801
                10905330
                38426365
                de2cf07a-d73e-490d-9306-9d1b74aa4725
                © 2024 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

                History
                : 02 February 2024
                : 05 January 2024
                : 04 February 2024
                Page count
                Figures: 2, Tables: 7, Pages: 13, Words: 7258
                Funding
                Funded by: Skin Research Institute of Singapore, Agency for Science, Technology and Research (A*STAR) , doi 10.13039/501100001348;
                Award ID: H17/01/a0/0Y9
                Funded by: National Healthcare Group , doi 10.13039/501100010754;
                Award ID: PHG20/S/X/1/1
                Funded by: National Medical Research Council , doi 10.13039/501100001349;
                Award ID: FLWSHP19nov‐0015
                Categories
                Original Article
                Original Articles
                Custom metadata
                2.0
                March 2024
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.3.8 mode:remove_FC converted:01.03.2024

                Emergency medicine & Trauma
                amputation,diabetic foot ulcer,health impact assessment,interdisciplinary communication,lower extremity

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