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      Clinical and economic outcomes of a multidisciplinary team approach in a lower extremity amputation prevention programme for diabetic foot ulcer care in an Asian population: A case‐control study

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          Abstract

          Present guidelines recommend a multidisciplinary team (MDT) approach to diabetic foot ulcer (DFU) care, but relevant data from Asia are lacking. We aim to evaluate the clinical and economic outcomes of an MDT approach in a lower extremity amputation prevention programme (LEAPP) for DFU care in an Asian population. We performed a case‐control study of 84 patients with DFU between January 2017 and October 2017 (retrospective control) vs 117 patients with DFU between December 2017 and July 2018 (prospective LEAPP cohort). Comparing the clinical outcomes between the retrospective cohort and the LEAPP cohort, there was a significant decrease in mean time from referral to index clinic visit (38.6 vs 9.5 days, P < .001), increase in outpatient podiatry follow‐up (33% vs 76%, P < .001), decrease in 1‐year minor amputation rate (14% vs 3%, P = .007), and decrease in 1‐year major amputation rate (9% vs 3%, P = .05). Simulation of cost avoidance demonstrated an annualised cost avoidance of USD $1.86m (SGD $2.5m) for patients within the LEAPP cohort. In conclusion, similar to the data from Western societies, an MDT approach in an Asian population, via a LEAPP for patients with DFU, demonstrated a significant reduction in minor and major amputation rates, with annualised cost avoidance of USD $1.86m.

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          Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

          Globally, the number of people with diabetes mellitus has quadrupled in the past three decades, and diabetes mellitus is the ninth major cause of death. About 1 in 11 adults worldwide now have diabetes mellitus, 90% of whom have type 2 diabetes mellitus (T2DM). Asia is a major area of the rapidly emerging T2DM global epidemic, with China and India the top two epicentres. Although genetic predisposition partly determines individual susceptibility to T2DM, an unhealthy diet and a sedentary lifestyle are important drivers of the current global epidemic; early developmental factors (such as intrauterine exposures) also have a role in susceptibility to T2DM later in life. Many cases of T2DM could be prevented with lifestyle changes, including maintaining a healthy body weight, consuming a healthy diet, staying physically active, not smoking and drinking alcohol in moderation. Most patients with T2DM have at least one complication, and cardiovascular complications are the leading cause of morbidity and mortality in these patients. This Review provides an updated view of the global epidemiology of T2DM, as well as dietary, lifestyle and other risk factors for T2DM and its complications.
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            Diabetic Foot Ulcers and Their Recurrence.

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              The STROBE guidelines

              An observational study is a type of epidemiological study design, which can take the form of a cohort, a case–control, or a cross-sectional study. When presenting observational studies in manuscripts, an author needs to ascertain a clear presentation of the work and provide the reader with appropriate information to enable critical appraisal of the research. The Strengthening the Reporting of Observational studies in Epidemiology (STROBE) guidelines were created to aid the author in ensuring high-quality presentation of the conducted observational study. The original articles publishing the STROBE guidelines together with their bibliographies were identified and thoroughly reviewed. These guidelines consist of 22 checklist items that the author needs to fulfil before submitting the manuscript to a journal. The STROBE guidelines were created to aid the authors in presenting their work and not to act as a validation tool for the conducted study or as a framework to conduct an observational study on. The authors complying with these guidelines are more likely to succeed in publishing their observational study work in a journal.
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                Author and article information

                Contributors
                huiling_liew@ttsh.com.sg
                Journal
                Int Wound J
                Int Wound J
                10.1111/(ISSN)1742-481X
                IWJ
                International Wound Journal
                Blackwell Publishing Ltd (Oxford, UK )
                1742-4801
                1742-481X
                06 August 2021
                May 2022
                : 19
                : 4 ( doiID: 10.1111/iwj.v19.4 )
                : 765-773
                Affiliations
                [ 1 ] Vascular Surgery Service, Department of General Surgery Tan Tock Seng Hospital Singapore
                [ 2 ] Lee Kong Chian School of Medicine Centre for Population Health Sciences Nayang Technological University Singapore
                [ 3 ] Skin Research Institute of Singapore Agency for Science, Technology and Research Singapore
                [ 4 ] Department of Podiatry Tan Tock Seng Hospital Singapore
                [ 5 ] Wound and Stoma Care, Nursing Specialty Tan Tock Seng Hospital Singapore
                [ 6 ] Health Services and Outcomes Research National Healthcare Group Singapore
                [ 7 ] Department of Endocrinology Woodlands Health Campus Singapore
                [ 8 ] Department of Endocrinology Tan Tock Seng Hospital Singapore
                Author notes
                [*] [* ] Correspondence

                Huiling Liew, Department of Endocrinology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433.

                Email: huiling_liew@ 123456ttsh.com.sg

                Author information
                https://orcid.org/0000-0003-2289-5266
                https://orcid.org/0000-0002-0956-5759
                Article
                IWJ13672
                10.1111/iwj.13672
                9013583
                34363329
                1368cf85-9d31-4313-807a-2d059e1e3894
                © 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

                History
                : 28 July 2021
                : 17 June 2021
                : 28 July 2021
                Page count
                Figures: 3, Tables: 4, Pages: 9, Words: 5550
                Funding
                Funded by: Agency for Science, Technology and Research (A*STAR) , doi 10.13039/501100001348;
                Award ID: H19/01/a0/PP9
                Categories
                Original Article
                Original Articles
                Custom metadata
                2.0
                May 2022
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.1.4 mode:remove_FC converted:17.04.2022

                Emergency medicine & Trauma
                diabetic foot ulcers,diabetic limb salvage,health economics,lower extremity amputation,multidisciplinary team

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