6
views
0
recommends
+1 Recommend
1 collections
    0
    shares

      Authors - publish your SDGs-related research with EDP Sciences. Find out more.

      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Wine and health: A review of its benefits to human health

      BIO Web of Conferences
      EDP Sciences

      Read this article at

      ScienceOpenPublisher
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Modern society seeks to consume foods that can treat and prevent disease, as well as increase longevity, and in this context stand out functional foods rich in antioxidant compounds with proven health benefits, as well as beverages that bring benefits to the health and are widely used by the population, such as wine. Wine has always been linked in some way to the history of man, either because it is a beverage with its own flavor and personality or because of the health benefits it brings. Studies carried out throughout the world show that wine, taken in a moderate amount, contributes to the health of the human organism, increasing the quality and the life time, being the polyphenols the main compounds present in the wine responsible for this contribution. In this context, the objective of this study is to carry out a bibliographical review on the main researches and studies carried out with the theme wine and health, with emphasis on the beneficial effect of the phenolic composition of red wines, and thus contribute to the dissemination of the benefits of regular consumption and wine to human health.

          Related collections

          Most cited references15

          • Record: found
          • Abstract: not found
          • Book: not found

          Handbook of Enology

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Resveratrol: A molecule whose time has come? And gone?

            Resveratrol (3,5,4'-trihydroxystilbene) is the parent compound of a family of molecules, including glucosides and polymers, existing in cis and trans configurations in a narrow range of spermatophytes of which vines, peanuts and pines are the prime representatives. Its synthesis from p-coumaroyl CoA and malonyl CoA is induced by stress, injury, infection or UV-irradiation, and it is classified as a phytoalexin anti-fungicide conferring disease resistance in the plant kingdom. In vitro, ex vivo and animal experiments have shown that it possesses many biological attributes that favour protection against atherosclerosis, including antioxidant activity, modulation of hepatic apolipoprotein and lipid synthesis, inhibition of platelet aggregation as well as the production of pro-atherogenic eicosanoids by human platelets and neutrophils. Red wine represents its main source in the human diet, and it has been proposed as a major constituent of the polyphenol fraction to which the health benefits of red wine consumption have been attributed. The past several years have witnessed intense research devoted to its measurement in wine and the factors likely to promote its enrichment in this beverage. Up to the present, conclusive evidence for its absorption by human subjectsin biologically significant amounts is lacking, and it is questionable (but not yetexcluded) that its powerful and beneficial in vitro activities are reproduced as a consequence of sustained moderate red wine consumption.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Anti-inflammatory activities of resveratrol in the brain: role of resveratrol in microglial activation.

              Neuroinflammation is an important contributor to pathogenesis of neurological disorders, with microglial activation as a hallmark of neuroinflammation. Microglia serve the role of immune surveillance under normal conditions, but after brain damage or exposure to inflammation, microglia are activated and secrete pro-inflammatory and neurotoxic mediators. Sustained production of these factors contributes to neuronal damage. Therefore, inhibition of microglia-mediated neuroinflammation may become a promising therapeutic target for neurological disorders. Resveratrol, a non-flavonoid polyphenol rich in red wine and grapes, has beneficial health effects from its antioxidant, anticancer and anti-inflammatory properties. Recently, resveratrol has been shown to protect against various neurological disorders in experimental models, including brain ischemia, seizures, and neurodegenerative disease models. This minireview summarized the anti-inflammatory activities of resveratrol in the brain from both in vivo and in vitro studies, and highlighted the inhibition of activated microglia as a potential mechanism of neuroprotection. The release of various pro-inflammatory factors, the production of reactive oxygen species, and the activation of signal pathways leading to neuroinflammation were discussed in relation to microglial activation. Taken together, microglia are an important target for anti-inflammatory activities of resveratrol in the brain. (c) 2010 Elsevier B.V. All rights reserved.
                Bookmark

                Author and article information

                Journal
                BIO Web of Conferences
                BIO Web Conf.
                EDP Sciences
                2117-4458
                2019
                February 19 2019
                2019
                : 12
                : 04001
                Article
                10.1051/bioconf/20191204001
                d293592e-08a6-4c8c-8546-c0fbfa220eec
                © 2019

                http://creativecommons.org/licenses/by/4.0/

                History

                Comments

                Comment on this article