In Silico Screening and Molecular Dynamic Study of Nonsynonymous Single Nucleotide Polymorphisms Associated with Kidney Stones in the SLC26A6 Gene.

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Abstract

SLC26A6 is a multifunctional anion transporter with a critical physiological role in the transport of oxalate anions. Recognizing a genetic variant of SLC26A6 would advance our understanding of oxalate transport in the formation of calcium oxalate stones.

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Journal ID (iso-abbrev): J. Urol.

Title: The Journal of urology

Publisher: Elsevier BV

ISSN (Electronic): 1527-3792

ISSN (Print): 0022-5347

Publication date (Electronic): Jul 2016

Volume: 196

Issue: 1

Affiliations

[1 ] Department of Biochemistry and Cell Biology, School of Life Science, Liaoning University, Shenyang, People's Republic of China; Research Center for Computer Simulating and Information Processing of Bio-macromolecules of Liaoning Province, Shenyang, People's Republic of China.

[2 ] Department of Biochemistry and Cell Biology, School of Life Science, Liaoning University, Shenyang, People's Republic of China.

[3 ] Department of Cell Biology and Genetics, Shenyang Medical College, Shenyang, People's Republic of China.

[4 ] Research Center for Computer Simulating and Information Processing of Bio-macromolecules of Liaoning Province, Shenyang, People's Republic of China.

[5 ] Department of Cell Biology and Genetics, Shenyang Medical College, Shenyang, People's Republic of China; Key Laboratory of Environment and Population Health of Liaoning Education Ministry, Shenyang Medical College, Shenyang, People's Republic of China; China-Japan Kidney Stone Research Center, Shenyang, People's Republic of China. Electronic address: gaobingdr@hotmail.com.

Article

Publisher Item ID: S0022-5347(16)00134-8

DOI: 10.1016/j.juro.2016.01.093

PubMed ID: 26812303

SO-VID: cb5b13ab-f848-4c65-93b4-3a7fc4a356f2

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Keywords: SLC26A6 protein, human,computer simulation,kidney calculi,oxalates,polymorphism, single nucleotide

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Keywords: SLC26A6 protein, human, computer simulation, kidney calculi, oxalates, polymorphism, single nucleotide

In Silico Screening and Molecular Dynamic Study of Nonsynonymous Single Nucleotide Polymorphisms Associated with Kidney Stones in the SLC26A6 Gene.

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