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      Review of surgical devices using small aperture optics

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          Abstract

          Small aperture optics work by blocking unfocused peripheral light rays while allowing central light rays to focus on the retina. This pinhole effect creates an extended depth of focus and has been used in presbyopia correction, improving intermediate and near vision without markedly affecting distance vision. Another beneficial effect of small aperture optics is reducing aberrations caused by irregular corneas or irregular pupils. The first small aperture surgical device was the Kamra corneal inlay used on the nondominant eyes of presbyopic emmetropes. The pinhole concept was also adapted into the IC-8 intraocular lens (IOL) for presbyopia correction during cataract surgery and by the XtraFocus piggyback device to lessen unwanted aberrations in eyes with irregular corneas or pupils. The IC-8 IOL can be placed monocularly or binocularly with mini-monovision for further near vision improvement. The XtraFocus piggyback device can be placed either in the sulcus or capsular bag. The aim of this literature review is to synthesize evidence on the efficacy, safety, and patient-reported outcomes on surgical devices utilizing small aperture optics. A comprehensive search on PubMed was conducted with the keywords “small aperture optics,” “small aperture corneal inlay,” “small aperture IOL,” “Kamra corneal inlay,” “IC-8 IOL,” and “XtraFocus.” In this review, we describe the progression of small aperture surgical devices, patient criteria, visual outcomes, complications, satisfaction, and recommendations for surgical success.

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          Most cited references37

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          Intracorneal inlay to correct presbyopia: Long-term results.

          To evaluate the long-term visual results of Acufocus ACI-7000 (now Kamra) intracorneal inlay implantation in presbyopic phakic patients. Beyoğlu Eye Training and Research Hospital, Istanbul, Turkey. Clinical trial. This study comprised patients with emmetropic or post-laser in situ keratomileusis (LASIK) presbyopia. Patients had an uncorrected near visual acuity (UNVA) of 20/40 or worse, correctable to 20/25 or better at distance. The inlay was implanted on the stromal bed after the LASIK flap was relifted or a flap created. The inlay was centered on the presurgical position of the first Purkinje reflex. The main outcome measures were distance and near vision and the complication rate. The study enrolled 39 patients aged 45 to 60 years. At the 4-year follow-up, all patients (N = 22) had 2 or more lines of improvement in UNVA with no significant loss in distance vision. The mean final UNVA was 20/20 (Jaeger [J1]); 96% of patients could read J3 or better. The uncorrected distance acuity was 20/40 or better in all eyes. Five patients had cataract progression, and 2 had a change in refractive status. No eye with an intracorneal inlay had intraoperative complications during cataract extraction. Four inlays were explanted during the study. There were no severe corneal complications that affected final vision. Intracorneal inlay implantation was an effective, safe, and reversible procedure for the long-term surgical treatment of presbyopia. Crown Copyright © 2011. Published by Elsevier Inc. All rights reserved.
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            Extended depth-of-focus technology in intraocular lenses.

            The extended depth-of-focus (EDOF) intraocular lens (IOL) is an emerging technology that is designed to improve range of vision, especially at intermediate distances. In this review, we describe the clinical performance of 4 emerging EDOF IOL technologies; that is, small aperture, bioanalogic, diffractive optics, and nondiffractive optical manipulations. The American Academy of Ophthalmology generated a consensus statement for EDOF IOLs that provided benchmarks and recommendations for classifying an implant as an EDOF IOL as well as standardized testing criteria for evaluating performance. Although many types of EDOF technologies are being developed, there are important differences in their performance that require further testing and evaluation.
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              Small-aperture corneal inlay for the correction of presbyopia: 3-year follow-up.

              To report the 3-year postoperative safety and efficacy outcomes of the Acufocus corneal inlay. University Eye Clinic, Paracelsus Medical University, Salzburg, Austria. Prospective nonrandomized noncomparative cohort study. The corneal inlay was implanted in the nondominant eye of naturally emmetropic presbyopic patients. Refraction, uncorrected near (UNVA), intermediate (UIVA), and distance (UDVA) visual acuities; corrected distance visual acuity (CDVA); contrast sensitivity; visual fields; subjective patient satisfaction and symptoms; and operative and postoperative adverse events and complications were evaluated. The study enrolled 32 patients. The mean UNVA improved from Jaeger (J) 6 preoperatively to J1 at 3 years and the mean UIVA, from 20/40 to 20/25, respectively. At 3 years, 97% of eyes had a UNVA of J3 or better and 91% had a UIVA of 20/32 or better. The mean UDVA was 20/20, with all eyes achieving 20/32 or better. Nine eyes (28.3%) lost 1 line of CDVA, 1 eye (3.1%) lost more than 2 lines (3.8 lines), and 3 eyes (9.3%) gained 1 line. No inlay was explanted, and no inflammatory reactions were observed. At 3 years, 15.6% of patients reported severe night-vision problems and 6.3% (versus 87.5% preoperatively) reported being dependent on reading glasses. These 3-year results support the safety and efficacy of the corneal inlay to correct presbyopia in naturally emmetropic presbyopic patients. However, despite a significant gain in UNVA and UIVA, 28.3% of patients lost 1 line of CDVA. Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.
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                Author and article information

                Journal
                Taiwan J Ophthalmol
                Taiwan J Ophthalmol
                TJO
                Taiwan Journal of Ophthalmology
                Wolters Kluwer - Medknow (India )
                2211-5056
                2211-5072
                Jul-Sep 2022
                07 January 2022
                : 12
                : 3
                : 282-294
                Affiliations
                [1]Asian Eye Institute, Makati City, Philippines
                Author notes
                [* ] Address for correspondence: Dr. Robert Edward T. Ang, Asian Eye Institute, 8 th Floor PHINMA Plaza, Rockwell Center, Makati City, Philippines. E-mail: angbobby@ 123456hotmail.com
                Article
                TJO-12-282
                10.4103/tjo.tjo_45_21
                9558464
                36248074
                9607f32a-81e2-4ae0-b4ae-be0cdcd183b0
                Copyright: © 2022 Taiwan J Ophthalmol

                This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

                History
                : 15 August 2021
                : 05 October 2021
                Categories
                Review Article

                complex corneas,extended depth of focus,ic-8,irregular pupils,kamra,presbyopia,small aperture,xtrafocus

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