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      Chitosan: a unique polysaccharide for drug delivery.

      Drug Development and Industrial Pharmacy
      Administration, Oral, Animals, Chemistry, Pharmaceutical, Chitin, analogs & derivatives, chemistry, Chitosan, Delayed-Action Preparations, Dosage Forms, Drug Carriers, Drug Delivery Systems, Excipients, Humans, Liposomes, Microspheres, Pharmaceutical Vehicles, Tablets

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          Abstract

          The aim of this review is to give an insight into the many potential applications of chitosan as a pharmaceutical drug carrier. The first part of this review concerns the principal uses of chitosan as an excipient in oral formulations (particularly as a direct tableting agent) and as a vehicle for parenteral drug delivery devices. The use of chitosan to manufacture sustained-release systems deliverable by other routes (nasal, ophthalmic, transdermal, and implantable devices) is discussed in the second part.

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