Catalpol alleviates ovalbumin-induced asthma in mice: Reduced eosinophil infiltration in the lung.

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Abstract

Radix Rehmanniae Preparata is a traditional Chinese herbal medicine used to treat asthma, and catalpol is one of the main active ingredients in this herb. In the present study, the effects of catalpol on asthma and the underlying mechanism were explored.

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Journal

Journal ID (iso-abbrev): Int. Immunopharmacol.

Title: International immunopharmacology

Publisher: Elsevier BV

ISSN (Electronic): 1878-1705

ISSN (Print): 1567-5769

Publication date (Electronic): Feb 2017

Volume: 43

Affiliations

[1 ] The Second Department of Paediatrics, the First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, People's Republic of China.

[2 ] Department of Pharmacy, the First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, People's Republic of China.

[3 ] The First Department of Paediatrics, the First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, People's Republic of China.

[4 ] Department of Endemic Disease, the Second Affiliated Hospital of Harbin Medical University, Harbin 150001, People's Republic of China.

[5 ] The Second Department of Paediatrics, the First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, People's Republic of China. Electronic address: wangh306@sina.com.

Article

Publisher Item ID: S1567-5769(16)30504-5

DOI: 10.1016/j.intimp.2016.12.011

PubMed ID: 27992791

SO-VID: 88c8e1dd-93ed-4cf5-aade-30a2f778e0b5

History

Keywords: IL-5Rα,Eotaxin,Eosinophils,Catalpol,CCR3,Asthma

Data availability:

Keywords: IL-5Rα, Eotaxin, Eosinophils, Catalpol, CCR3, Asthma

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