Articles in acute lung injury, in vitro cell models, cell co-cultures and inflamation of the lung.
Hallmarks of acute lung innjury include dysfunction of the alveolar-capillary membrane resulting in increased vascular permeability, an influx of inflammatory cells into the lung and a local pro-coagulant state. The syndrome has a mortality rate of approximately 35% and usually requires invasive mechanical ventilation. Improved animal models and the development of human in vivo and ex vivo models are therefore required.
Main image credit: | https://www.frontiersin.org/articles/10.3389/fimmu.2019.00821/full |
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ScienceOpen disciplines: | Toxicology, Cell biology, Respiratory medicine |
Keywords: | cell culture, in vitro models, lung models, inflamation |
DOI: | 10.14293/S2199-1006.1.SOR-MED.CL2WYFZ.v1 |