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      Bioinspired Environment‐Adaptable and Ultrasensitive Multifunctional Electronic Skin for Human Healthcare and Robotic Sensations

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          Abstract

          Multifunctional electronic skins (e‐skins) that can sense various stimuli have demonstrated increasing potential in many fields. However, most e‐skins are human‐oriented that cannot work in hash environments such as high temperature, underwater, and corrosive chemicals, impairing their applications, especially in human‐machine interfaces, intelligent machines, robotics, and so on. Inspired by the crack‐shaped sensory organs of spiders, an environmentally robust and ultrasensitive multifunctional e‐skin is developed. By developing a polyimide‐based metal crack‐localization strategy, the device has excellent environment adaptability since polyimide has high thermal stability and chemical durability. The localized cracked part serves as an ultrasensitive strain sensing unit, while the non‐cracked serpentine part is solely responsible for temperature. Since the two units are made of the same material and process, the signals are decoupled easily. The proposed device is the first multifunctional e‐skin that can be used in harsh environments, therefore is of great potential for both human and robot‐oriented applications.

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          Most cited references70

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          The capsaicin receptor: a heat-activated ion channel in the pain pathway.

          Capsaicin, the main pungent ingredient in 'hot' chilli peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. We have used an expression cloning strategy based on calcium influx to isolate a functional cDNA encoding a capsaicin receptor from sensory neurons. This receptor is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. The cloned capsaicin receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.
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            Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels.

            Mechanical stimuli drive many physiological processes, including touch and pain sensation, hearing, and blood pressure regulation. Mechanically activated (MA) cation channel activities have been recorded in many cells, but the responsible molecules have not been identified. We characterized a rapidly adapting MA current in a mouse neuroblastoma cell line. Expression profiling and RNA interference knockdown of candidate genes identified Piezo1 (Fam38A) to be required for MA currents in these cells. Piezo1 and related Piezo2 (Fam38B) are vertebrate multipass transmembrane proteins with homologs in invertebrates, plants, and protozoa. Overexpression of mouse Piezo1 or Piezo2 induced two kinetically distinct MA currents. Piezos are expressed in several tissues, and knockdown of Piezo2 in dorsal root ganglia neurons specifically reduced rapidly adapting MA currents. We propose that Piezos are components of MA cation channels.
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              Is Open Access

              Skin-inspired highly stretchable and conformable matrix networks for multifunctional sensing

              Mechanosensation electronics (or Electronic skin, e-skin) consists of mechanically flexible and stretchable sensor networks that can detect and quantify various stimuli to mimic the human somatosensory system, with the sensations of touch, heat/cold, and pain in skin through various sensory receptors and neural pathways. Here we present a skin-inspired highly stretchable and conformable matrix network (SCMN) that successfully expands the e-skin sensing functionality including but not limited to temperature, in-plane strain, humidity, light, magnetic field, pressure, and proximity. The actualized specific expandable sensor units integrated on a structured polyimide network, potentially in three-dimensional (3D) integration scheme, can also fulfill simultaneous multi-stimulus sensing and achieve an adjustable sensing range and large-area expandability. We further construct a personalized intelligent prosthesis and demonstrate its use in real-time spatial pressure mapping and temperature estimation. Looking forward, this SCMN has broader applications in humanoid robotics, new prosthetics, human–machine interfaces, and health-monitoring technologies.
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                Author and article information

                Contributors
                Journal
                Small
                Small
                Wiley
                1613-6810
                1613-6829
                October 2023
                June 10 2023
                October 2023
                : 19
                : 41
                Affiliations
                [1 ] State Key Laboratory of High‐performance Precision Manufacturing Dalian University of Technology Dalian Liaoning 116024 China
                [2 ] State Key Laboratory of Structural Analysis for Industrial Equipment Dalian University of Technology Dalian 116024 China
                [3 ] State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University of Science and Technology Wuhan 430074 China
                [4 ] National Key Laboratory of Science and Technology on Micro and Nano Fabrication School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Shanghai 200240 China
                [5 ] Institute of Flexible Electronics Northwestern Polytechnical University Xi'an 710072 China
                [6 ] Department of Engineering Mechanics Dalian University of Technology Dalian 116024 China
                [7 ] Key Laboratory for Micro/Nano Technology and System of Liaoning Province Dalian University of Technology Dalian Liaoning 116024 China
                Article
                10.1002/smll.202304004
                7ef00818-76ae-4c3e-b4ce-1da9e295b30d
                © 2023

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