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      The complete digital workflow in fixed prosthodontics: a systematic review

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          Abstract

          Background

          The continuous development in dental processing ensures new opportunities in the field of fixed prosthodontics in a complete virtual environment without any physical model situations. The aim was to compare fully digitalized workflows to conventional and/or mixed analog-digital workflows for the treatment with tooth-borne or implant-supported fixed reconstructions.

          Methods

          A PICO strategy was executed using an electronic (MEDLINE, EMBASE, Google Scholar) plus manual search up to 2016–09-16 focusing on RCTs investigating complete digital workflows in fixed prosthodontics with regard to economics or esthetics or patient-centered outcomes with or without follow-up or survival/success rate analysis as well as complication assessment of at least 1 year under function. The search strategy was assembled from MeSH-Terms and unspecific free-text words: {((“Dental Prosthesis” [MeSH]) OR (“Crowns” [MeSH]) OR (“Dental Prosthesis, Implant-Supported” [MeSH])) OR ((crown) OR (fixed dental prosthesis) OR (fixed reconstruction) OR (dental bridge) OR (implant crown) OR (implant prosthesis) OR (implant restoration) OR (implant reconstruction))} AND {(“Computer-Aided Design” [MeSH]) OR ((digital workflow) OR (digital technology) OR (computerized dentistry) OR (intraoral scan) OR (digital impression) OR (scanbody) OR (virtual design) OR (digital design) OR (cad/cam) OR (rapid prototyping) OR (monolithic) OR (full-contour))} AND {(“Dental Technology” [MeSH) OR ((conventional workflow) OR (lost-wax-technique) OR (porcelain-fused-to-metal) OR (PFM) OR (implant impression) OR (hand-layering) OR (veneering) OR (framework))} AND {((“Study, Feasibility” [MeSH]) OR (“Survival” [MeSH]) OR (“Success” [MeSH]) OR (“Economics” [MeSH]) OR (“Costs, Cost Analysis” [MeSH]) OR (“Esthetics, Dental” [MeSH]) OR (“Patient Satisfaction” [MeSH])) OR ((feasibility) OR (efficiency) OR (patient-centered outcome))}.

          Assessment of risk of bias in selected studies was done at a ‘trial level’ including random sequence generation, allocation concealment, blinding, completeness of outcome data, selective reporting, and other bias using the Cochrane Collaboration tool. A judgment of risk of bias was assigned if one or more key domains had a high or unclear risk of bias. An official registration of the systematic review was not performed.

          Results

          The systematic search identified 67 titles, 32 abstracts thereof were screened, and subsequently, three full-texts included for data extraction. Analysed RCTs were heterogeneous without follow-up. One study demonstrated that fully digitally produced dental crowns revealed the feasibility of the process itself; however, the marginal precision was lower for lithium disilicate (LS2) restorations (113.8 μm) compared to conventional metal-ceramic (92.4 μm) and zirconium dioxide (ZrO2) crowns (68.5 μm) ( p < 0.05). Another study showed that leucite-reinforced glass ceramic crowns were esthetically favoured by the patients (8/2 crowns) and clinicians (7/3 crowns) ( p < 0.05). The third study investigated implant crowns. The complete digital workflow was more than twofold faster (75.3 min) in comparison to the mixed analog-digital workflow (156.6 min) (p < 0.05). No RCTs could be found investigating multi-unit fixed dental prostheses (FDP).

          Conclusions

          The number of RCTs testing complete digital workflows in fixed prosthodontics is low. Scientifically proven recommendations for clinical routine cannot be given at this time. Research with high-quality trials seems to be slower than the industrial progress of available digital applications. Future research with well-designed RCTs including follow-up observation is compellingly necessary in the field of complete digital processing.

          Electronic supplementary material

          The online version of this article (10.1186/s12903-017-0415-0) contains supplementary material, which is available to authorized users.

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          Most cited references18

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          Comparison of digital and conventional impression techniques: evaluation of patients’ perception, treatment comfort, effectiveness and clinical outcomes

          Background The purpose of this study was to compare two impression techniques from the perspective of patient preferences and treatment comfort. Methods Twenty-four (12 male, 12 female) subjects who had no previous experience with either conventional or digital impression participated in this study. Conventional impressions of maxillary and mandibular dental arches were taken with a polyether impression material (Impregum, 3 M ESPE), and bite registrations were made with polysiloxane bite registration material (Futar D, Kettenbach). Two weeks later, digital impressions and bite scans were performed using an intra-oral scanner (CEREC Omnicam, Sirona). Immediately after the impressions were made, the subjects’ attitudes, preferences and perceptions towards impression techniques were evaluated using a standardized questionnaire. The perceived source of stress was evaluated using the State-Trait Anxiety Scale. Processing steps of the impression techniques (tray selection, working time etc.) were recorded in seconds. Statistical analyses were performed with the Wilcoxon Rank test, and p < 0.05 was considered significant. Results There were significant differences among the groups (p < 0.05) in terms of total working time and processing steps. Patients stated that digital impressions were more comfortable than conventional techniques. Conclusions Digital impressions resulted in a more time-efficient technique than conventional impressions. Patients preferred the digital impression technique rather than conventional techniques.
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            Digital vs. conventional implant prosthetic workflows: a cost/time analysis.

            The aim of this prospective cohort trial was to perform a cost/time analysis for implant-supported single-unit reconstructions in the digital workflow compared to the conventional pathway.
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              The clinical accuracy of single crowns exclusively fabricated by digital workflow--the comparison of two systems.

              The purpose of the study was to compare the accuracy of crowns exclusively fabricated by the digital workflow of two systems. The null hypothesis stated was: Both systems do not differ with respect to marginal and internal accuracy. In 14 patients, 13 molars and 1 premolar were prepared. Each preparation was scanned intraorally with two different digital impression systems, Lava COS and Cerec AC. On the basis of these data, Lava DVS crowns [DVS] and Vita Rapid Layering Technique crowns [RLT] were fabricated, respectively. Both systems contained of a zirconia framework and a digitally fabricated silicate ceramic veneering. The marginal and internal fit of the crowns was documented by a replica technique. The replicas were examined under microscope with a magnification of ×200. The Wilcoxon signed rank test was applied in order to test if the values of the two systems showed significant differences at p ≤ 0.05. The results were as follows in micrometers (±standard deviation): at the marginal gap, 51 (±38) for [DVS] and 83 (±51) for [RLT]; mid-axial, 130 (±56) for [DVS] and 128 (±66) for [RLT]; axio-occlusal, 178 (±55) for [DVS] and 230 (±71) for [RLT]; and centro-occlusal, 181 (±41) for [DVS] and 297 (±76) for [RLT]. According to the Wilcoxon signed rank test, the results differed significantly at the marginal, axio-occlusal, and centro-occlusal gaps. The null hypothesis had to be rejected. The exclusively digital workflow on the basis of intraoral digital impressions delivered clinically satisfying results for single crowns with both systems.
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                Author and article information

                Contributors
                +41 (0)31 / 632-9994 , tim.joda@zmk.unibe.ch
                zarone@unina.it
                ferrarm@gmail.com
                Journal
                BMC Oral Health
                BMC Oral Health
                BMC Oral Health
                BioMed Central (London )
                1472-6831
                19 September 2017
                19 September 2017
                2017
                : 17
                : 124
                Affiliations
                [1 ]ISNI 0000 0001 0726 5157, GRID grid.5734.5, Section for Digital Reconstructive Technology + Implant Dentistry [DiRecT + ID], Department of Reconstructive Dentistry, School of Dental Medicine, , University of Bern, ; Freiburgstr. 7, 3010 Bern, Switzerland
                [2 ]ISNI 0000 0001 0790 385X, GRID grid.4691.a, Department of Prosthodontics, School of Dental Medicine, , University of Napoli, ; Naples, Italy
                [3 ]ISNI 0000 0004 1757 4641, GRID grid.9024.f, Department of Prosthodontics & Dental Materials, School of Dental Medicine, , University of Siena, ; Siena, Italy
                [4 ]ISNI 0000 0004 1936 8403, GRID grid.9909.9, Department of Restorative Dentistry, School of Dental Medicine, , University of Leeds, ; Leeds, UK
                [5 ]Department of Reconstructive Dentistry, University Center for Dental Medicine, Basel, Switzerland
                Article
                415
                10.1186/s12903-017-0415-0
                5606018
                28927393
                6b4d49a3-8015-4651-b365-fcb020a6f488
                © The Author(s). 2017

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 14 June 2017
                : 13 September 2017
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2017

                Dentistry
                systematic review,fixed prosthodontics,tooth-bourne,implant-supported,complete digital workflow

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