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      Aerobic training decreases bronchial hyperresponsiveness and systemic inflammation in patients with moderate or severe asthma: a randomised controlled trial.

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          Abstract

          The benefits of aerobic training for the main features of asthma, such as bronchial hyperresponsiveness (BHR) and inflammation, are poorly understood. We investigated the effects of aerobic training on BHR (primary outcome), serum inflammatory cytokines (secondary outcome), clinical control and asthma quality of life (Asthma Quality of Life Questionnaire (AQLQ)) (tertiary outcomes).

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          Author and article information

          Journal
          Thorax
          Thorax
          1468-3296
          0040-6376
          Aug 2015
          : 70
          : 8
          Affiliations
          [1 ] Departments of Clinical Immunology and Allergy, School of Medicine, University of São Paulo, Sao Paulo, Brazil.
          [2 ] Department of Physical Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil.
          [3 ] Pulmonary Division, Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, Brazil.
          [4 ] Department of Medicine, Laboratory of Experimental Therapeutics (LIM-20), School of Medicine, University of Sao Paulo, São Paulo, Brazil.
          Article
          thoraxjnl-2014-206070
          10.1136/thoraxjnl-2014-206070
          26063507
          5f1bc3b4-2555-48df-aacc-119f045c2a19
          Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
          History

          Asthma,Exercise,Pulmonary Rehabilitation
          Asthma, Exercise, Pulmonary Rehabilitation

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