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      Neuraxial anesthesia decreases postoperative systemic infection risk compared with general anesthesia in knee arthroplasty.

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          Abstract

          Surgical stress has been shown to result in immune disturbance. Neuraxial anesthesia (NA) has long been hypothesized to blunt undesired surgical insults and thus limit immune compromise and improve surgical outcomes. We hypothesized that NA would decrease postoperative infectious complications compared with general anesthesia (GA) among knee arthroplasty patients.

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          Author and article information

          Journal
          Anesth. Analg.
          Anesthesia and analgesia
          1526-7598
          0003-2999
          Oct 2013
          : 117
          : 4
          Affiliations
          [1 ] Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19104. Jiabin.Liu@uphs.upenn.ed.
          Article
          ANE.0b013e3182a1bf1c NIHMS498552
          10.1213/ANE.0b013e3182a1bf1c
          24023024
          3ff3ea32-d27e-4bc0-89e9-484d05d93b6d
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