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      An artificially-intelligent cornea with tactile sensation enables sensory expansion and interaction

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          Abstract

          We demonstrate an artificially-intelligent cornea that can assume the functions of the native human cornea such as protection, tactile perception, and light refraction, and possesses sensory expansion and interactive functions. These functions are realized by an artificial corneal reflex arc that is constructed to implement mechanical and light information coding, information processing, and the regulation of transmitted light. Digitally-aligned, long and continuous zinc tin oxide (ZTO) semiconductor fabric patterns were fabricated as the active channels of the artificial synapse, which are non-toxic, heavy-metal-free, low-cost, and ensure superior comprehensive optical properties (transmittance >99.89%, haze <0.36%). Precisely-tuned crystal-phase structures of the ZTO fibers enabled reconfigurable synaptic plasticity, which is applicable to encrypted communication and associative learning. This work suggests new strategies for the tuning of synaptic plasticity and the design of visual neuroprosthetics, and has important implications for the development of neuromorphic electronics and for visual restoration.

          Abstract

          Existing artificial corneas can assume partial functions of the human cornea, but sense reconstruction remains a challenge. Qu et al. develop an artificially-intelligent cornea with tactile sensation that enables sensory expansion and interaction.

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              Global Survey of Corneal Transplantation and Eye Banking.

              Corneal transplantation restores visual function when visual impairment caused by a corneal disease becomes too severe. It is considered the world's most frequent type of transplantation, but, to our knowledge, there are no exhaustive data allowing measurement of supply and demand, although such data are essential in defining local, national, and global strategies to fight corneal blindness.
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                Author and article information

                Contributors
                wentao@nankai.edu.cn
                Journal
                Nat Commun
                Nat Commun
                Nature Communications
                Nature Publishing Group UK (London )
                2041-1723
                7 November 2023
                7 November 2023
                2023
                : 14
                : 7181
                Affiliations
                [1 ]Institute of Photoelectronic Thin Film Devices and Technology, Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin, College of Electronic Information and Optical Engineering, Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education, Smart Sensing Interdisciplinary Science Center, Nankai University, ( https://ror.org/01y1kjr75) Tianjin, 300350 China
                [2 ]Shenzhen Research Institute of Nankai University, ( https://ror.org/01y1kjr75) Shenzhen, 518000 China
                Author information
                http://orcid.org/0000-0002-1054-6037
                Article
                42240
                10.1038/s41467-023-42240-3
                10630301
                37935671
                1d0cb654-5a91-469a-a04c-53809ec6b06f
                © The Author(s) 2023

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 25 April 2023
                : 3 October 2023
                Funding
                Funded by: National Science Fund for Distinguished Young Scholars of China (T2125005) National Key R&D Program of China (2022YFE0198200, 2022YFA1204500, 2022YFA1204504) Tianjin Science Foundation for Distinguished Young Scholars (19JCJQJC61000) Shenzhen Science and Technology Project (JCYJ20210324121002008) National Natural Science Foundation of China (62204131) China Postdoctoral Science Foundation (2023T160336)
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                © Springer Nature Limited 2023

                Uncategorized
                electronic properties and materials,electronic devices
                Uncategorized
                electronic properties and materials, electronic devices

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