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      Role of distraction osteogenesis in craniomaxillofacial surgery

      review-article
      ,
      Innovative Surgical Sciences
      De Gruyter
      dentofacial anomaly, gradual expansion, Ilizarov method

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          Abstract

          In the field of orthopedic surgery, distraction osteogenesis (DO) is well known for limb lengthening procedures or secondary corrective surgery in the fracture treatment of the extremities. The principle of gradual expansion of bone and surrounding soft tissues as originally described by G.A. Ilizarov is also applicable to the craniofacial skeleton when growth deficiency is present, and the patients affected by craniofacial or dentofacial anomalies may require distraction procedures. The surgical management is comparable. After osteotomy and the mounting of a specific craniomaxillofacial distraction device, active distraction is started after a latency phase of several days, with a distraction rate of up to 1 mm/day until the desired amount of distraction has been achieved. Subsequently, distractors are locked to provide appropriate stability within the distraction zone for callus mineralization during the consolidation phase of 3–6 months, which is followed by a further remodeling of the bony regenerate. After 14 years of clinical application, the role and significance of craniomaxillofacial DO are discussed after reviewing the files of all patients who were treated by craniomaxillofacial distraction procedures.

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          Most cited references28

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          The tension-stress effect on the genesis and growth of tissues: Part II. The influence of the rate and frequency of distraction.

          To assess the influence of both the rate and the frequency of distraction on osteogenesis during limb elongation, a canine tibia was used with various combinations of distraction rates (0.5 mm, 1.0 mm, or 2.0 mm per day) and distraction frequencies (one step per day, four steps per day, 60 steps per day). The distractions were performed after both open osteotomy and closed osteoclasis. Histomorphic and biochemical studies were conducted on the elongated osseous tissue, fascia, skeletal muscle, smooth muscle, blood vessels, nerves, and skin. It was determined that distraction at a rate of 0.5 mm per day often led to premature consolidation of the lengthening bone, while a distraction rate of 2.0 mm per day often resulted in undesirable changes within elongating tissues. A distraction rate of 1.0 mm per day led to the best results. It was also observed that the greater the distraction frequency, the better the outcome. With optimum preservation of periosseous tissues, bone marrow, and blood supply at the time of osteotomy, stability of external fixation, and 1.0 mm per day of distraction in four steps, osteogenesis within the distraction gap of an elongating bone takes place by the formation of a physislike structure, in which new bone forms in parallel columns extending in both directions from a central growth zone. The growth plate that forms under the influence of tension-stress has features of both physeal and intramembranous ossification, yet is neither; instead, the distraction regenerated bone is unique, providing numerous applications in clinical traumatology, orthopedics, and other medical disciplines.
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            Clinical Application of the Tension-Stress Effect for Limb Lengthening

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              The tension-stress effect on the genesis and growth of tissues. Part I. The influence of stability of fixation and soft-tissue preservation

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                Author and article information

                Contributors
                Journal
                Innov Surg Sci
                Innov Surg Sci
                iss
                iss
                iss
                Innovative Surgical Sciences
                De Gruyter
                2364-7485
                08 December 2016
                December 2016
                : 1
                : 2
                : 97-103
                Affiliations
                deptDepartment of Craniomaxillofacial Surgery , universityCharité Universitaetsmedizin Berlin, Centre 9 for Traumatology and Reconstructive Surgery, Campus Virchow Klinikum , Berlin, Germany
                Article
                iss-2016-0027
                10.1515/iss-2016-0027
                6753988
                1a52cc5f-1478-45c0-b20d-88593d0fe130
                ©2016 Ernst N., Adolphs N., published by De Gruyter, Berlin/Boston

                This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

                History
                : 11 October 2016
                : 06 November 2016
                Page count
                Pages: 11
                Categories
                Review

                dentofacial anomaly,gradual expansion,ilizarov method

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