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      Risk factors of urinary tract infection through demographic and laboratory markers among benign prostate hyperplasia patients: a single-center study

      , , , ,
      Folia Medica
      Pensoft Publishers

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          Abstract

          Introduction: Prostate enlargement known as benign prostatic hyperplasia (BPH) increases the risk of infection in the urinary tract by obstructing or blocking the prostatic portion of the urethra. This disease becomes more common as people age. Aim: To determine differences in the risk of urinary tract infection based on demographics and laboratory markers in patients with benign prostate hyperplasia. Materials and methods: The present study is quantitative analytical observational research. Patients from Vita Insani Hospital’s Urology Polyclinic in Pematangsiantar during 2021–2023 made up the study’s population. In sampling, we used the purposive sampling technique. Results: Medical records were used to gather data, which were then subjected to univariate and bivariate analyses using SPSS. The present study found that there were statistically significant differences between the neutrophil lymphocyte and the platelet-lymphocyte ratios in the incidence of urinary tract infections among BPH populations (p<0.05), while other studies documented that risk factors such as monocyte-to-lymphocyte ratio, catheter use, comorbidity status, and renal functions (urea, creatinine, and GFR levels) did not show significant differences (p>0.05). Conclusion: It is expected that health workers, especially nurses in hospitals can provide information, always monitor signs of infection and apply aseptic procedures in performing catheter insertion actions to BPH patients to avoid urinary tract infections.

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          Most cited references22

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          Epidemiology of clinical benign prostatic hyperplasia

          Kok Lim (2017)
          Clinical benign prostatic hyperplasia (BPH) is one of the most common diseases in ageing men and the most common cause of lower urinary tract symptoms (LUTS). The prevalence of BPH increases after the age of 40 years, with a prevalence of 8%–60% at age 90 years. Some data have suggested that there is decreased risk among the Asians compared to the western white population. Genetics, diet and life style may play a role here. Recent reports suggest the strong relationship of clinical BPH with metabolic syndrome and erectile dysfunction, as well as the possible role of inflammation as a cause of the prostatic hyperplasia. Lifestyle changes including exercise and diet are important strategies in controlling this common ailment.
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            Diabetes-associated infections: development of antimicrobial resistance and possible treatment strategies

            Diabetes mellitus is associated with various types of infections notably skin, mucous membrane, soft tissue, urinary tract, respiratory tract and surgical and/or hospital-associated infections. The reason behind this frequent association with infections is an immunocompromised state of diabetic patient because uncontrolled hyperglycemia impairs overall immunity of diabetic patient via involvement of various mechanistic pathways that lead to the diabetic patient as immunocompromised. There are specific microbes that are associated with each type of infection and their presence indicates specific type of infections. For instance, E. coli and Klebsiella are the most common causative pathogens responsible for the development of urinary tract infections. Diabetic-foot infections commonly occur in diabetic patients. In this article, we have mainly focused on the association of diabetes mellitus with various types of bacterial infections and the pattern of resistance against antimicrobial agents that are frequently used for the treatment of diabetes-associated infections. Moreover, we have also summarized the possible treatment strategies against diabetes-associated infections.
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              Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia (BPH): AUA Guideline Amendment 2023

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                Author and article information

                Contributors
                (View ORCID Profile)
                (View ORCID Profile)
                Journal
                Folia Medica
                FM
                Pensoft Publishers
                1314-2143
                0204-8043
                December 31 2024
                December 31 2024
                : 66
                : 6
                : 818-824
                Article
                10.3897/folmed.66.e137393
                0e79b620-2e9d-4c8a-8f65-42272b439797
                © 2024

                http://creativecommons.org/licenses/by/4.0/

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