For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
42
views
213
references
 Top references
cited by
33
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      261
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Characteristics, Occurrence, Detection and Detoxification of Aflatoxins in Foods and Feeds

      review-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Mycotoxin contamination continues to be a food safety concern globally, with the most toxic being aflatoxins. On-farm aflatoxins, during food transit or storage, directly or indirectly result in the contamination of foods, which affects the liver, immune system and reproduction after infiltration into human beings and animals. There are numerous reports on aflatoxins focusing on achieving appropriate methods for quantification, precise detection and control in order to ensure consumer safety. In 2012, the International Agency for Research on Cancer (IARC) classified aflatoxins B1, B2, G1, G2, M1 and M2 as group 1 carcinogenic substances, which are a global human health concern. Consequently, this review article addresses aflatoxin chemical properties and biosynthetic processes; aflatoxin contamination in foods and feeds; health effects in human beings and animals due to aflatoxin exposure, as well as aflatoxin detection and detoxification methods.

          Related collections

          Most cited references213

          • Record: found
          • Abstract: found
          • Article: not found

          Fungal secondary metabolism - from biochemistry to genomics.

          Nancy Keller, Geoffrey Turner, Joan W. Bennett (2005)
          Much of natural product chemistry concerns a group of compounds known as secondary metabolites. These low-molecular-weight metabolites often have potent physiological activities. Digitalis, morphine and quinine are plant secondary metabolites, whereas penicillin, cephalosporin, ergotrate and the statins are equally well known fungal secondary metabolites. Although chemically diverse, all secondary metabolites are produced by a few common biosynthetic pathways, often in conjunction with morphological development. Recent advances in molecular biology, bioinformatics and comparative genomics have revealed that the genes encoding specific fungal secondary metabolites are clustered and often located near telomeres. In this review, we address some important questions, including which evolutionary pressures led to gene clustering, why closely related species produce different profiles of secondary metabolites, and whether fungal genomics will accelerate the discovery of new pharmacologically active natural products.
          Article 0 comments Cited 490 times – based on 0 reviews     Review now
          Article has an altmetric score of 23
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            FAOSTAT

            (2025)
            Article 0 comments Cited 214 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              Aflatoxin B1 contamination in maize in Europe increases due to climate change

              P Battilani, P Toscano, H. J. Van der Fels-Klerx … (2016)
              Climate change has been reported as a driver for emerging food and feed safety issues worldwide and its expected impact on the presence of mycotoxins in food and feed is of great concern. Aflatoxins have the highest acute and chronic toxicity of all mycotoxins; hence, the maximal concentration in agricultural food and feed products and their commodities is regulated worldwide. The possible change in patterns of aflatoxin occurrence in crops due to climate change is a matter of concern that may require anticipatory actions. The aim of this study was to predict aflatoxin contamination in maize and wheat crops, within the next 100 years, under a +2 °C and +5 °C climate change scenario, applying a modelling approach. Europe was virtually covered by a net, 50 × 50 km grids, identifying 2254 meshes with a central point each. Climate data were generated for each point, linked to predictive models and predictions were run consequently. Aflatoxin B1 is predicted to become a food safety issue in maize in Europe, especially in the +2 °C scenario, the most probable scenario of climate change expected for the next years. These results represent a supporting tool to reinforce aflatoxin management and to prevent human and animal exposure.
              Article 0 comments Cited 211 times – based on 0 reviews     Review now
              Article has an altmetric score of 56
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Foods
                Journal ID (iso-abbrev): Foods
                Journal ID (publisher-id): foods
                Title: Foods
                Publisher: MDPI
                ISSN (Electronic): 2304-8158
                Publication date (Electronic): 18 May 2020
                Publication date Collection: May 2020
                Volume: 9
                Issue: 5
                Electronic Location Identifier: 644
                Affiliations
                [1 ]Department of Biotechnology, Sari Agricultural Science and Natural Resource University, 9th km of Farah Abad Road, Mazandaran 48181-68984, Iran; nazhand.ah@ 123456gmail.com
                [2 ]CREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Roma, Italy; alessandra.durazzo@ 123456crea.gov.it (A.D.); massimo.lucarini@ 123456crea.gov.it (M.L.)
                [3 ]Faculty of Pharmacy of University of Coimbra, Azinhaga de Santa Comba, Polo III-Saúde, 3000-548 Coimbra, Portugal; souto.eliana@ 123456gmail.com
                [4 ]CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal
                [5 ]Department of Pharmacy, University of Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy
                Author notes
                [* ]Correspondence: asantini@ 123456unina.it ; Tel.: +39-81-253-9317
                Author information
                https://orcid.org/0000-0002-7747-9107
                https://orcid.org/0000-0002-9737-6017
                https://orcid.org/0000-0001-5505-3327
                Article
                Publisher ID: foods-09-00644
                DOI: 10.3390/foods9050644
                PMC ID: 7278662
                PubMed ID: 32443392
                SO-VID: 005ee3da-154f-4558-979e-64a1720832f8
                Copyright © © 2020 by the authors.
                License:

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                Date received : 21 March 2020
                Date accepted : 12 May 2020
                Categories
                Subject: Review

                Keywords: aflatoxins,mycotoxins,detoxification,food safety,health issue
                Data availability:
                Keywords: aflatoxins, mycotoxins, detoxification, food safety, health issue

                Comments

                Comment on this article

                scite_
                0
                0
                0
                0
                Smart Citations
                0
                0
                0
                0
                Citing PublicationsSupportingMentioningContrasting
                View Citations

                See how this article has been cited at scite.ai

                scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

                Similar content261

                See all similar

                Cited by33

                See all cited by

                Most referenced authors2,884

                See all reference authors