Clinical Significance of Tumour CD44v and MIST1 Expression in Patients With Non-small-cell Lung Cancer.

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Abstract

Cancer stem cells (CSCs) are involved in cancer metastasis and relapse. Therefore, identification of CSC biomarkers might help determine the success of a treatment. In this study, we examined the expression of four CSC markers: Cluster of differentiation 44 variant (CD44v), leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5), frizzled 7 (FZD7), and muscle, intestine and stomach expression 1 (MIST1), in cancer tissues of patients with non-small-cell lung cancer at >5 years after resection, and its clinical significance.

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Author and article information

Journal

Journal ID (iso-abbrev): Anticancer Res

Title: Anticancer research

Publisher: Anticancer Research USA Inc.

ISSN (Electronic): 1791-7530

ISSN (Print): 0250-7005

Publication date (Electronic): Nov 2020

Volume: 40

Issue: 11

Affiliations

[1 ] Department of Thoracic Surgery, Kanagawa Cancer Center, Yokohama, Japan.

[2 ] Department of Surgery, Yokohama City University, Yokohama, Japan.

[3 ] Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan oshima@kcch.jp.

[4 ] Kanagawa Cancer Center Research Institute, Yokohama, Japan.

[5 ] Department of Pathology, Kanagawa Cancer Center, Yokohama, Japan.

[6 ] Respiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.

Article

Publisher Item ID: 40/11/6407

DOI: 10.21873/anticanres.14662

PubMed ID: 33109579

SO-VID: 22e1f427-aec7-4b4c-98a3-fc2bc88e10c3

History

Keywords: prognostic marker,Non-small-cell lung cancer,cancer stem cell

Data availability:

Keywords: prognostic marker, Non-small-cell lung cancer, cancer stem cell

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