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      Mild cognitive impairment and deficits in instrumental activities of daily living: a systematic review.

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          Abstract

          There is a growing body of evidence that subtle deficits in instrumental activities of daily living (IADL) may be present in mild cognitive impairment (MCI). However, it is not clear if there are IADL domains that are consistently affected across patients with MCI. In this systematic review, therefore, we aimed to summarize research results regarding the performance of MCI patients in specific IADL (sub)domains compared with persons who are cognitively normal and/or patients with dementia.

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          The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

          Guy M McKhann, David S. Knopman, Howard Chertkow … (2011)
          The National Institute on Aging and the Alzheimer's Association charged a workgroup with the task of revising the 1984 criteria for Alzheimer's disease (AD) dementia. The workgroup sought to ensure that the revised criteria would be flexible enough to be used by both general healthcare providers without access to neuropsychological testing, advanced imaging, and cerebrospinal fluid measures, and specialized investigators involved in research or in clinical trial studies who would have these tools available. We present criteria for all-cause dementia and for AD dementia. We retained the general framework of probable AD dementia from the 1984 criteria. On the basis of the past 27 years of experience, we made several changes in the clinical criteria for the diagnosis. We also retained the term possible AD dementia, but redefined it in a manner more focused than before. Biomarker evidence was also integrated into the diagnostic formulations for probable and possible AD dementia for use in research settings. The core clinical criteria for AD dementia will continue to be the cornerstone of the diagnosis in clinical practice, but biomarker evidence is expected to enhance the pathophysiological specificity of the diagnosis of AD dementia. Much work lies ahead for validating the biomarker diagnosis of AD dementia. Copyright © 2011. Published by Elsevier Inc.
          Article 0 comments Cited 2995 times – based on 0 reviews     Review now
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            “Mini-mental state”

            Marshal Folstein, Susan Folstein, Paul McHugh (1975)
            Article 0 comments Cited 2634 times – based on 0 reviews     Review now
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              Assessment of Older People: Self-Maintaining and Instrumental Activities of Daily Living

              M P Lawton, E M Brody (1969)
              Article 0 comments Cited 1914 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (iso-abbrev): Alzheimers Res Ther
                Title: Alzheimer's research & therapy
                Publisher: Springer Science and Business Media LLC
                ISSN: 1758-9193
                Publication date (Electronic): 2015
                Volume: 7
                Issue: 1
                Affiliations
                [1 ] Network Aging Research, Heidelberg University, Bergheimer Str. 20, 69115 Heidelberg, Germany ; Department of Geriatric Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Square J 5, 68159 Mannheim, Germany.
                [2 ] Department of Geriatric Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Square J 5, 68159 Mannheim, Germany.
                [3 ] Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, 20502 Malmö, Sweden.
                [4 ] Kingshill Research Centre, Victoria Hospital, 53 Downs Way, Swindon, SN3 6BW UK.
                [5 ] Hon Senior Lecturer in Psychiatry at the University of Dundee, Murray Royal Hospital, Perth, PH2 7BH UK.
                [6 ] Centre des Maladies Cognitives et Comportementales (IM2A), Institut du Cerveau et de la Moelle épinière (ICM), UMR-S975, Université Pierre et Marie Curie- Paris6, AP-HP, Hôpital de la Salpêtrière, 47 boulevard de l'Hôpital, 75013 Paris, France.
                [7 ] Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Alfred Nobels allé 23, 14183 Huddinge, Sweden.
                [8 ] Institute of Health and Nursing Science, Charité Center 1 for Health and Human Sciences, Augustenburger Platz 1, 13353 Berlin, Germany.
                [9 ] Center for Health Services Research in Medicine, Department of Psychiatry and Psychotherapy, Friedrich-Alexander-University Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany.
                [10 ] Department of Neurology, Centre for Cognitive Impairments, University Medical Centre Ljubljana, Zaloška cesta 2, 1000 Ljubljana, Slovenia.
                [11 ] Scottish Dementia Clinical Research Network, Murray Royal Hospital, Perth, PH2 7BH UK.
                [12 ] Institute of Gerontology and Geriatrics, University of Perugia, via Brunamonti 51, 06122 Perugia, Italy.
                [13 ] Alzheimer's Disease and Other Cognitive Disorders Unit, ICN, Hospital Clínic i Universitari, IDIBAPS, Villarroel 170, Barcelona, 08036 Spain.
                [14 ] Division of Occupational Therapy, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Fack 23200, 14183 Huddinge, Sweden.
                [15 ] Department of Geriatrics, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6525 GC Nijmegen, the Netherlands.
                [16 ] Department of Clinical Neurosciences, University Hospital Pellegrin, Place Amélie Raba-Léon, 33000 Bordeaux, France.
                [17 ] INSERM U1171, CHU, Memory Clinic, University of Lille, rue Emile Laine, 59037 Lille, France.
                [18 ] University of Bordeaux, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, 33000 Bordeaux, France ; INSERM, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, 33000 Bordeaux, France.
                [19 ] Memory Clinic, Department of Neurology, University of Liège, allée du 6 Août 8, 4000 Liège, Belgium.
                [20 ] Alzheimer Center and Department of Epidemiology and Biostatistics, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
                [21 ] Department of Medical Psychology, Medical University of Lodz, 5 Sterling St, 90-425 Lodz, Poland.
                [22 ] Memory Clinic, University Center for Medicine of Aging Basel, Felix Platter Hospital, Schanzenstr. 55, CH-4031 Basel, Switzerland.
                [23 ] 3rd Department of Neurology, Aristotle University, Despere 3, Thessaloniki, 54621 Greece.
                [24 ] Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society (NVS), Center for Alzheimer Research, Karolinska Institutet, 14157 Huddinge, Sweden.
                Article
                Publisher Item ID: 99
                DOI: 10.1186/s13195-015-0099-0
                PMC ID: 4374414
                PubMed ID: 25815063
                SO-VID: e0f18d82-382e-40f8-b491-9d77d89f5da5
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