Contributors
Lauren Brady:
ORCID: https://orcid.org/0000-0002-7876-5164
Role: InvestigationRole: MethodologyRole: Writing – original draftRole: Writing –
review & editing
Brian Hayes: Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Writing – review
& editing
Gráinne Sheill: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Anne-Marie Baird: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Emer Guinan: Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Writing – review
& editing
Bryan Stanfill: Role: Formal analysisRole: Writing – review & editing
Tatjana Vlajnic: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Orla Casey: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Verena Murphy: Role: InvestigationRole: MethodologyRole: Writing – review & editing
John Greene: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Emma H. Allott: Role: Formal analysisRole: Writing – review & editing
Juliette Hussey: Role: ConceptualizationRole: Writing – review & editing
Fidelma Cahill: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Mieke Van Hemelrijck: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Nicola Peat: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Lorelei Mucci: Role: ConceptualizationRole: Writing – review & editing
Moya Cunningham: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Liam Grogan: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Thomas Lynch: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Rustom P. Manecksha:
ORCID: https://orcid.org/0000-0003-3437-744X
Role: InvestigationRole: MethodologyRole: Writing – review & editing
John McCaffrey: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Dearbhaile O’Donnell: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Orla Sheils: Role: ConceptualizationRole: Writing – review & editing
John O’Leary: Role: ConceptualizationRole: Writing – review & editing
Sarah Rudman: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Ray McDermott: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Stephen Finn: Role: ConceptualizationRole: InvestigationRole: MethodologyRole: SupervisionRole:
Writing – review & editing
Luis Costa: Role: Editor
Journal
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS One
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
18
December
2020
Publication date Collection: 2020
Volume: 15
Issue: 12
Electronic Location Identifier: e0243928
Affiliations
[1
]
Department of Histopathology and Morbid Anatomy, Trinity Translational Medicine Institute,
Trinity College Dublin, Dublin, Ireland
[2
]
Department of Histopathology, Cork University Hospital, Cork, Ireland
[3
]
Department of Pathology, University College Cork, Cork, Ireland
[4
]
Discipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland
[5
]
School of Medicine, Trinity College Dublin, Dublin, Ireland
[6
]
Pacific Northwest National Laboratory, Richland, Washington, United States of America
[7
]
Institute of Pathology, University Hospital Basel, Basel, Switzerland
[8
]
Cancer Trials Ireland, Dublin, Ireland
[9
]
Centre for Cancer Research and Cell Biology, Queen’s University Belfast, Belfast,
Northern Ireland, United Kingdom
[10
]
King’s College London, School of Cancer and Pharmaceutical Sciences, Translational
Oncology and Urology (TOUR), London, United Kingdom
[11
]
Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom
[12
]
Harvard T.H. Chan school of Public Health, Boston, Massachusetts, United States of
America
[13
]
Department of Radiation Oncology, St Luke’s Hospital, Dublin, Ireland
[14
]
Department of Oncology, Beaumont Hospital, Dublin, Ireland
[15
]
Department of Urology, St James’s Hospital, Dublin, Ireland
[16
]
Department of Surgery, Trinity College Dublin, Dublin, Ireland
[17
]
Department of Oncology, Mater Misericordiae Hospital, Dublin, Ireland
[18
]
HOPE Directorate, St James’s Hospital, Dublin, Ireland
[19
]
Department of Histopathology, St James’s Hospital, Dublin, Ireland
[20
]
Department of Oncology, Tallaght University Hospital, Dublin, Ireland
Hospital de Santa Maria, PORTUGAL
Author notes
Competing Interests: All authors have completed the ICMJE uniform disclosure form at
www.icmje.org/coi_disclosure.pdf and declare: support from the World Cancer Research fund. AMB declares board membership
of LUCE which has received support from Abbvie, Amgen, BMS, BI, Lilly, Merck, MSD,
Novartis, Pfizer, Roche and Takeda, advisory boards for BMS, Takeda and Pfizer and
personal fees and non-financial support from Roche, personal fees and non-financial
support from MSD, outside the submitted work. BS reports funding from Trinity College
Dublin throughout the conduct of this study. EG and MVH report membership of the editorial
board of BMC Cancer. RMD reports personal fees from Clovis, grants and personal fees
from Pfizer, grants from Amgen, personal fees and other from Bristol Myers Squibb,
other from Merck, Bayer and Janssen and grants from Celgene outside the submitted
work. SF reports personal fees and non-financial support from Pfizer, grants, personal
fees and non-financial support from MSD, personal fees and non-financial support from
Roche, grants, personal fees and non-financial support from Astellas, outside the
submitted work. This does not alter our adherence to PLOS ONE policies on sharing
data and materials.
Author information
Article
Publisher ID:
PONE-D-20-21500
DOI: 10.1371/journal.pone.0243928
PMC ID: 7748139
PubMed ID: 33338056
SO-VID: ff05e364-6aea-4915-8098-b2250bf6631a
Copyright © © 2020 Brady et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 14
July
2020
Date
accepted
: 28
November
2020
Page count
Figures: 3,
Tables: 3,
Pages: 15
Funding
Funded by: funder-id http://dx.doi.org/10.13039/100013743, World Cancer Research Fund International;
Award ID: 2012/1003
Award Recipient
:
Stephen Finn
This research was sponsored by Cancer Trials Ireland. Author SF received funding from
the World Cancer Research Fund (
https://www.wcrf.org/; grant number 2012/1003). The funders had no role in the collection of specimens
or analysis of data throughout the study duration, and had no role in preparation
or review of this manuscript for publication.
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