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Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases.
W Jeffrey Allard
1 ,
Jeri Matera ,
M Craig Miller ,
Madeline Repollet ,
Mark C Connelly ,
Chandra Rao ,
Arjan G J Tibbe ,
Jonathan W Uhr ,
Leon W M M Terstappen
Oct 15 2004
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Abstract
The purpose of this study was to determine the accuracy, precision, and linearity of the CellSearch system and evaluate the number of circulating tumor cells (CTCs) per 7.5 mL of blood in healthy subjects, patients with nonmalignant diseases, and patients with a variety of metastatic carcinomas.