Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids.

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Abstract

Lupus nephritis (LN) is a serious complication of systemic lupus erythematosus (SLE). All current treatment regimens include oral steroids, which are associated with severe adverse events and long-term damage. We have piloted a steroid-avoiding protocol (rituxilup) for the treatment of biopsy-proven active International Society of Nephrology/Renal Pathology Society (ISN/RPS) class III, IV, or class V LN.

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Author and article information

Journal

Journal ID (iso-abbrev): Ann Rheum Dis

Title: Annals of the rheumatic diseases

Publisher: BMJ

ISSN (Electronic): 1468-2060

ISSN (Print): 0003-4967

Publication date (Electronic): Aug 2013

Volume: 72

Issue: 8

Affiliations

[1 ] Imperial College NHS Healthcare Trust Lupus Centre, Hammersmith Hospital, London, UK.

Article

Publisher Item ID: annrheumdis-2012-202844

DOI: 10.1136/annrheumdis-2012-202844

PubMed ID: 23740227

SO-VID: fe5b41dd-5904-4a14-9713-43ac329067f3

History

Keywords: B cells,Corticosteroids,Lupus Nephritis,Treatment

Data availability:

Keywords: B cells, Corticosteroids, Lupus Nephritis, Treatment

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