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      Present and Future of Surface-Enhanced Raman Scattering

      review-article
      , , , § , , , # , 7 , 8 , 9 , 10 ,   11 , 12 , 13 , 14 , 15 , 16 , 15 , 16 , 17 , 18 , , 19 , 20 , 18 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , , # , 7 , 30 , 31 , 32 , 30 , 33 , 15 , 16 , 34 , 35 , 36 , 37 , 38 , 39 , 39 , 15 , 16 , 23 , 40 , 32 , 41 , 25 , 42 , 43 , 44 , 32 , 41 , 45 , 46 , 47 , 28 , 29 , 48 , 10 , 49 , 50 , , 51 ,
      ACS Nano
      American Chemical Society
      surface-enhanced Raman scattering , biosensing, SERS tags, chemosensors, nanomedicine, TERS, SEIRA, charge transfer, hot electrons, catalysis
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          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The discovery of the enhancement of Raman scattering by molecules adsorbed on nanostructured metal surfaces is a landmark in the history of spectroscopic and analytical techniques. Significant experimental and theoretical effort has been directed toward understanding the surface-enhanced Raman scattering (SERS) effect and demonstrating its potential in various types of ultrasensitive sensing applications in a wide variety of fields. In the 45 years since its discovery, SERS has blossomed into a rich area of research and technology, but additional efforts are still needed before it can be routinely used analytically and in commercial products. In this Review, prominent authors from around the world joined together to summarize the state of the art in understanding and using SERS and to predict what can be expected in the near future in terms of research, applications, and technological development. This Review is dedicated to SERS pioneer and our coauthor, the late Prof. Richard Van Duyne, whom we lost during the preparation of this article.

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          Most cited references947

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          The Fano resonance in plasmonic nanostructures and metamaterials.

          Since its discovery, the asymmetric Fano resonance has been a characteristic feature of interacting quantum systems. The shape of this resonance is distinctively different from that of conventional symmetric resonance curves. Recently, the Fano resonance has been found in plasmonic nanoparticles, photonic crystals, and electromagnetic metamaterials. The steep dispersion of the Fano resonance profile promises applications in sensors, lasing, switching, and nonlinear and slow-light devices.
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            Single-molecule strong coupling at room temperature in plasmonic nanocavities

            Emitters placed in an optical cavity experience an environment that changes their coupling to light. In the weak-coupling regime light extraction is enhanced, but more profound effects emerge in the single-molecule strong-coupling regime where mixed light-matter states form1,2. Individual two-level emitters in such cavities become non-linear for single photons, forming key building blocks for quantum information systems as well as ultra-low power switches and lasers3–6. Such cavity quantum electrodynamics has until now been the preserve of low temperatures and complex fabrication, severely compromising their use5,7,8. Here, by scaling the cavity volume below 40 nm3 and using host-guest chemistry to align 1-10 protectively-isolated methylene-blue molecules, we reach the strong-coupling regime at room temperature and in ambient conditions. Dispersion curves from >50 plasmonic nanocavities display characteristic anticrossings, with Rabi frequencies of 300 meV for 10 molecules decreasing to 90 meV for single molecules, matching quantitative models. Statistical analysis of vibrational spectroscopy time-series and dark-field scattering spectra provide evidence of single-molecule strong coupling. This dressing of molecules with light can modify photochemistry, opening up the exploration of complex natural processes such as photosynthesis9 and pathways towards manipulation of chemical bonds10.
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              Plasmon-induced hot carrier science and technology.

              The discovery of the photoelectric effect by Heinrich Hertz in 1887 set the foundation for over 125 years of hot carrier science and technology. In the early 1900s it played a critical role in the development of quantum mechanics, but even today the unique properties of these energetic, hot carriers offer new and exciting opportunities for fundamental research and applications. Measurement of the kinetic energy and momentum of photoejected hot electrons can provide valuable information on the electronic structure of materials. The heat generated by hot carriers can be harvested to drive a wide range of physical and chemical processes. Their kinetic energy can be used to harvest solar energy or create sensitive photodetectors and spectrometers. Photoejected charges can also be used to electrically dope two-dimensional materials. Plasmon excitations in metallic nanostructures can be engineered to enhance and provide valuable control over the emission of hot carriers. This Review discusses recent advances in the understanding and application of plasmon-induced hot carrier generation and highlights some of the exciting new directions for the field.
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                Author and article information

                Journal
                ACS Nano
                ACS Nano
                nn
                ancac3
                ACS Nano
                American Chemical Society
                1936-0851
                1936-086X
                03 September 2019
                28 January 2020
                : 14
                : 1
                : 28-117
                Affiliations
                []CIC biomaGUNE and CIBER-BBN , Paseo de Miramón 182, Donostia-San Sebastián 20014, Spain
                []Materials Physics Center (CSIC-UPV/EHU), and Donostia International Physics Center , Paseo Manuel de Lardizabal 5, Donostia-San Sebastián 20018, Spain
                [§ ]Departamento de Química Física e Inorgánica and EMaS, Universitat Rovira i Virgili , Tarragona 43007, Spain
                []ICREA-Institució Catalana de Recerca i Estudis Avançats , Passeig Lluís Companys 23, Barcelona 08010, Spain
                []School of Chemical and Physical Sciences, Victoria University of Wellington , PO Box 600, Wellington 6140, New Zealand
                [# ]The MacDiarmid Institute for Advanced Materials and Nanotechnology , PO Box 600, Wellington 6140, New Zealand
                [7 ]The Dodd-Walls Centre for Quantum and Photonic Technologies , PO Box 56, Dunedin 9054, New Zealand
                [8 ]NanoPhotonics Centre, Cavendish Laboratory, University of Cambridge , Cambridge CB3 0HE, United Kingdom
                [9 ]Department of Materials and Chemistry and Biochemistry, University of California , Santa Barbara, California 93106-9510, United States
                [10 ]School of Chemistry and Chemical Engineering, Queen’s University of Belfast , Belfast BT9 5AG, United Kingdom
                [11 ]Department of Micro- and Nanotechnology, The Danish National Research Foundation and Villum Foundation’s Center for Intelligent Drug Delivery and Sensing Using Microcontainers and Nanomechanics, Technical University of Denmark , Kongens Lyngby 2800, Denmark
                [12 ]Department of Chemistry, University of Victoria , P.O. Box 3065, Victoria, BC V8W 3 V6, Canada
                [13 ]Center for Advanced Materials and Related Technologies, University of Victoria , Victoria, BC V8W 2Y2, Canada
                [14 ]Department of Chemistry, Chung-Ang University , Seoul 06974, South Korea
                [15 ]Leibniz Institute of Photonic Technology Jena - Member of the research alliance “Leibniz Health Technologies” , Albert-Einstein-Str. 9, Jena 07745, Germany
                [16 ]Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich-Schiller University Jena , Helmholtzweg 4, Jena 07745, Germany
                [17 ]Department of Materials Science and Engineering, Rutgers University , 607 Taylor Road, Piscataway New Jersey 08854, United States
                [18 ]Department of Pure and Applied Chemistry, University of Strathclyde , Technology and Innovation Centre, 99 George Street, Glasgow G1 1RD, United Kingdom
                [19 ]The Barcelona Institute of Science and Technology, Institut de Ciencies Fotoniques , Castelldefels (Barcelona) 08860, Spain
                [20 ]Department of Biochemistry, Institute of Integrative Biology, University of Liverpool , Biosciences Building, Crown Street, Liverpool L69 7ZB, United Kingdom
                [21 ]Department of Chemistry, University of Iowa , Iowa City, Iowa 52242, United States
                [22 ]Department of Chemistry, University of Minnesota , 207 Pleasant Street SE, Minneapolis, Minnesota 55455, United States
                [23 ]Kirchhoff Institute for Physics, University of Heidelberg , Im Neuenheimer Feld 227, Heidelberg 69120, Germany
                [24 ]Nano-Bioanalysis Research Group, Health Research Institute, National Institute of Advanced Industrial Science and Technology , Takamatsu, Kagawa 761-0395, Japan
                [25 ]Department of Physics, Chalmers University of Technology , Goteborg S412 96, Sweden
                [26 ]Department of Chemistry, Humboldt-Universität zu Berlin , Brook-Taylor-Str. 2, Berlin-Adlershof 12489, Germany
                [27 ]Department of Chemical Engineering, University of Michigan , Ann Arbor, Michigan 48109, United States
                [28 ]Key Lab of Synthetic and Biological Colloids, Ministry of Education, International Joint Research Laboratory for Biointerface and Biodetection, Jiangnan University , Wuxi, Jiangsu 214122, China
                [29 ]State Key Laboratory of Food Science and Technology, Jiangnan University , JiangSu 214122, China
                [30 ]Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University , 21 Nanyang Link, Singapore 637371, Singapore
                [31 ]Department of Materials Science and Engineering, Stanford University , Stanford, California 94305, United States
                [32 ]State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University , Xiamen 361005, China
                [33 ]Chair in Hybrid Nanosystems, Nanoinstitute Munich, Faculty of Physics, Ludwig-Maximilians-Universität München , Munich 80539, Germany
                [34 ]Department of Chemistry & Biochemistry, University of California Santa Barbara , Santa Barbara, California 93106-9510, United States
                [35 ]Department of Chemistry, Faculty of Science, Hokkaido University , North 10 West 8, Kita-ku, Sapporo, Hokkaido 060-0810, Japan
                [36 ]Department of Chemistry, Seoul National University , Seoul 08826, South Korea
                [37 ]Department of Bioengineering, University of Illinois at Urbana-Champaign , 1406 W. Green Street, Urbana, Illinois 61801, United States
                [38 ]Department of Chemistry, School of Science and Technology, Kwansei Gakuin University , Sanda, Hyogo 669-1337, Japan
                [39 ]Departamento de Química Física and CINBIO, University of Vigo , Vigo 36310, Spain
                [40 ]Department of Physics, Freie Universität Berlin , Berlin 14195, Germany
                [41 ]Department of Chemistry, Northwestern University , Evanston, Illinois 60208-3113, United States
                [42 ]Physical Chemistry I, Department of Chemistry and Center for Nanointegration Duisburg-Essen, University of Duisburg-Essen , Essen 45141, Germany
                [43 ]National Research Council Canada, Metrology Research Centre , Ottawa K1A0R6, Canada
                [44 ]School of Chemistry, Indian Institute of Science Education and Research Thiruvananthapuram , Vithura Thiruvananthapuram 695551, India
                [45 ]Fitzpatrick Institute for Photonics, Department of Biomedical Engineering, and Department of Chemistry, Duke University , 101 Science Drive, Box 90281, Durham, North Carolina 27708, United States
                [46 ]Department of Chemistry, College of Sciences, Northeastern University , Shenyang 110819, China
                [47 ]Department of Chemistry, Temple University , Philadelphia, Pennsylvania 19122, United States
                [48 ]School of Physics and Technology and Institute for Advanced Studies, Wuhan University , Wuhan 430072, China
                [49 ]School of Materials Science, Japan Advanced Institute of Science and Technology , Nomi, Ishikawa 923-1292, Japan
                [50 ]State Key Laboratory of Supramolecular Structure and Materials, Jilin University , Changchun 130012, China
                [51 ]Ikerbasque, Basque Foundation for Science , Bilbao 48013, Spain
                Author notes
                Article
                10.1021/acsnano.9b04224
                6990571
                31478375
                fd74057f-5162-4e14-a0bf-3c0a55cbeff7
                Copyright © 2019 American Chemical Society

                This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.

                History
                : 08 July 2019
                : 03 September 2019
                Categories
                Review
                Custom metadata
                nn9b04224
                nn9b04224

                Nanotechnology
                surface-enhanced raman scattering,biosensing,sers tags,chemosensors,nanomedicine,ters,seira,charge transfer,hot electrons,catalysis

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