Objective optical quality in eyes with customized selection of aspheric intraocular lens implantation

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Background

To compare the postoperative optical quality in eyes with customized selection and random selection of aspheric intraocular lens (IOL) implantation.

Methods

A prospective, nonrandomized study was implemented in adult cataract patients who underwent unilateral phacoemulsification with aspheric IOL implantation. Patients were allocated into two treatment groups: a customized group and a control group. In the customized group, the aspheric IOL selection was based on the corneal spherical aberration to enable the postoperative target ocular spherical aberration closest to zero; in the control group, the aspheric IOLs were chosen using a random strategy. Primary outcome measurements included the following objective optical quality assessments: higher-order aberrations obtained by a Hartmann-shack aberrometer at 4 mm and 6 mm pupil diameters; objective scatter index (OSI), modulation transfer function (MTF) cut-off, Strehl ratio (SR) and a simulated contrast visual acuity—optical quality analysis system value (OV) obtained by a double-pass system with a 4-mm aperture. Subjective visual acuity was measured as secondary outcome. All the patients were followed up for 3 months.

Results

Eighty-four patients in the customized group and 78 patients in the control group were evaluated. There was no significant difference in postoperative visual acuity between the two groups ( P > 0.05). Significantly less ocular higher-order aberrations were shown in the customized group ( P < 0.05). No significant difference was shown in OSI, MTF cut-off, SR and OV between the two groups ( P > 0.05).

Conclusions

Although customized selection of aspheric IOL implantation showed less postoperative ocular aberrations, it performed similarly to random selection of aspheric IOL implantation in terms of postoperative visual acuity, simulated contrast visual acuity, intraocular scatter, modulation transfer function and Strehl ratio.

Trial registration

Retrospectively registered on 07/06/2019. Registration number: ChiCTR1900024356.

Related collections

Most cited references 32

Record: found
Abstract: found
Article: not found

A new intraocular lens design to reduce spherical aberration of pseudophakic eyes.

Jack Holladay, Patricia A Piers, Gabor Koranyi … (2015)

The aim of this study was to design and evaluate in the laboratory a new intraocular lens (IOL) intended to provide superior ocular optical quality by reducing spherical aberration. Corneal topography measurements were performed on 71 cataract patients using an Orbscan I. The measured corneal surface shapes were used to determine the wavefront aberration of each cornea. A model cornea was then designed to reproduce the measured average spherical aberration. This model cornea was used to design IOLs having a fixed amount of negative spherical aberration that partially compensates for the average positive spherical aberration of the cornea. Theoretical and physical eye models were used to assess the expected improvement in optical quality of an eye implanted with this lens. Measurements of optical quality provided evidence that if this modified prolate IOL was centered within 0.4 mm and tilted less than 7 degrees, it would exceed the optical performance of a conventional spherical IOL. This improvement occurred without an apparent loss in depth of focus. A new IOL with a prolate anterior surface, designed to partially compensate for the average spherical aberration of the cornea, is intended to improve the ocular optical quality of pseudophakic patients.

0 comments Cited 67 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Repeatability of measurements with a double-pass system.

Alain Saad, Marc Saab, Damien Gatinel (2010)

To evaluate the repeatability of measurements with a double-pass system. Rothschild Foundation, Paris, France. Eyes were separated into 2 control groups ( 40 years), a post-refractive surgery group, and a cataract group. Measurements were performed using the Optical Quality Analysis System. The main outcome measures were the objective scattering index (OSI), the cutoff frequency of the modulation transfer function (MTF), and the Strehl ratio. The repeatability limit was obtained from the individual standard deviations. Forty-two eyes were evaluated. The mean OSI value was 0.47 +/- 0.11 (SD) in the younger control group, 1.73 +/- 0.26 in the older control group, 1.34 +/- 0.16 in the post-refractive surgery group, and 6.15 +/- 0.50 in the cataract group. The mean cutoff MTF value was 39.44 +/- 3.93 cycles per degree (cpd), 26.07 +/- 3.89 cpd, 28.34 +/- 2.84 cpd, and 13.3 +/- 1.69 cpd, respectively, and the mean Strehl ratio, 0.234 +/- 0.023, 0.146 +/- 0.021, 0.169 +/- 0.023, and 0.098 +/- 0.010, respectively. The repeatability limit for the whole population was 0.841 (33.5%) for the OSI, 8.499 (31.1%) for the cutoff MTF, and 0.051 (31%) for the Strehl ratio. The repeatability limit was good and equivalent for the OSI, the MTF, and the Strehl ratio values. There was a wide interval between the normal and pathologic threshold for OSI measurements, indicating that the reliability of the double-pass device complies with the requirements for quantitative assessment of scattering. No author has a financial or proprietary interest in any material or method mentioned. Copyright 2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

0 comments Cited 46 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Comparison of the retinal image quality with a Hartmann-Shack wavefront sensor and a double-pass instrument.

Fernando Díaz-Doutón, Antonio Benito, Jaume Pujol … (2006)

Wavefront sensors provide quite useful information on the optical quality of the eye. However, in eyes where very high-order aberrations and scattered light are prominent, wavefront sensors may overestimate retinal image quality. This study showed that, in those cases, the double-pass technique is a complementary tool for better estimation of ocular optical quality. A double-pass (DP) instrument was used, based on recording images of a point source in near-infrared light after reflection in the retina and double-pass through the ocular media. The aberrations were also measured with a prototype of near-infrared Hartmann-Shack (HS) wavefront sensor adapted to the clinical environment. From the wave aberrations, the modulation transfer function (MTF) was calculated (MTF_HS). The MTF was also obtained from the double-pass images (MTF_DP). Both techniques were applied in normal young subjects as the control and in three other groups of eyes: older subjects, after LASIK refractive surgery, and after IOL implantation. The MTFs obtained from DP and HS techniques were compared. In the group of normal eyes with low levels of intraocular scattering, these estimates were quite similar, indicating that both techniques captured well most of the optical degradation. However, in eyes where scatter was more predominant (e.g., early cataract, posterior capsular opacification after IOL implantation) the MTF provided by the HS sensor was always higher than the MTF obtained from DP. A single parameter was used to indicate the differences. In eyes with low scattering, DP and HS techniques provided similar estimates of the retinal image quality. However, in a patient's eye with mild to severe amount of scatter, wavefront sensors might overestimate image quality, whereas the DP technique produces a more accurate description of the optical quality, better correlated with the quality of vision.

0 comments Cited 44 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Contributors

Xuan Liao: aleexand@163.com

Chang-Jun Lan:

ORCID: http://orcid.org/0000-0002-1040-9622

eyelanchangjun@163.com

Journal

Journal ID (nlm-ta): BMC Ophthalmol

Journal ID (iso-abbrev): BMC Ophthalmol

Title: BMC Ophthalmology

Publisher: BioMed Central (London )

ISSN (Electronic): 1471-2415

Publication date (Electronic): 18 July 2019

Publication date PMC-release: 18 July 2019

Publication date Collection: 2019

Volume: 19

Electronic Location Identifier: 152

Affiliations

[1 ]ISNI 0000 0004 1758 177X, GRID grid.413387.a, Department of Ophthalmology, , Affiliated Hospital of North Sichuan Medical College, ; 1 Mao Yuan Nan Road, Nanchong, 637000 Sichuan China

[2 ]ISNI 0000 0004 1798 4472, GRID grid.449525.b, Department of Ophthalmology and Optometry, , North Sichuan Medical College, ; 1 Mao Yuan Nan Road, Nanchong, 637000 Sichuan China

Author information

Qing-Qing Tan http://orcid.org/0000-0002-3858-0528

Chang-Jun Lan http://orcid.org/0000-0002-1040-9622

Article

Publisher ID: 1162

DOI: 10.1186/s12886-019-1162-6

PMC ID: 6639902

PubMed ID: 31319806

SO-VID: fc735035-c391-42b4-8913-0b3a9e74e38c

License:

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

History

Date received : 4 April 2019

Date accepted : 9 July 2019

Funding

Funded by: FundRef http://dx.doi.org/10.13039/501100009564, Health and Family Planning Commission of Sichuan Province;

Award ID: 18ZD022

Award ID: 17PJ529

Award Recipient : Xuan Liao Chang-Jun Lan

Custom metadata

ScienceOpen disciplines: Ophthalmology & Optometry

Keywords: cataract,aspheric iol,customized,higher-order aberrations,oqas

Data availability:

ScienceOpen disciplines: Ophthalmology & Optometry

Keywords: cataract, aspheric iol, customized, higher-order aberrations, oqas

Comments

Comment on this article

scite_

Cited by 8

See all cited by

Most referenced authors 282

See all reference authors

Objective optical quality in eyes with customized selection of aspheric intraocular lens implantation

Read this article at

Abstract

Background

Methods

Results

Conclusions

Trial registration

Related collections

Karger: Ophthalmology

Most cited references 32

A new intraocular lens design to reduce spherical aberration of pseudophakic eyes.

Repeatability of measurements with a double-pass system.

Comparison of the retinal image quality with a Hartmann-Shack wavefront sensor and a double-pass instrument.

Author and article information

Contributors

Journal

Affiliations

Author information

Article

History

Funding

Categories

Custom metadata

Comments

Comment on this article

Similar content 231

Cited by 8

Most referenced authors 282