Comparative analysis of a presbyopia-correcting intraocular lens that combines extended depth-of-focus and bifocal profiles with a standard monofocal intraocular lens

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Abstract

Background

Recently, a new presbyopia-correcting intraocular lens (IOL) that combines extended depth-of-focus and bifocal profiles (ZFR00: Tecnis® Synergy®, Johnson & Johnson Vision, Santa Ana, CA, USA) has been established and several studies have been reported. We attempted to compare the performance with a standard IOL (ZCB00: Tecnis® monofocal, Johnson & Johnson Vision, Santa Ana, CA, USA) manufactured using the same material from the same company, which has been extensively used worldwide.

Methods

The medical records of patients undergoing cataract surgery with ZCB00 or ZFR00 implantation between March 2021 and September 2021 and with available 3-month visit data were reviewed. Uncorrected near, intermediate, and distance visual acuity (VA), corrected distance VA, and optical quality were the main outcome measures.

Results

This study included forty-six patients (64 eyes), with twenty-one patients (32 eyes) implanted with ZCB00 and twenty-five patients (32 eyes) implanted with ZFR00. The average age of the patients was 66.0 ± 10.1 (range: 40 to 82) and 65.1 ± 4.7 (range: 59 to 77) years in the ZCB00 and ZFR00 groups, respectively. The preoperative characteristics did not differ significantly between the two groups. Compared to the ZCB00 group, the ZFR00 group demonstrated significantly superior intermediate and near VA ( p < 0.001) at 3 months postoperatively. The ZFR00 group showed significantly lower objective measured optical quality than that in the ZCB00 group.

Conclusions

The ZFR00 exhibited a continuous range of vision and a smooth defocus curve, while the ZCB00 provided superior objective optical quality.

Supplementary Information

The online version contains supplementary material available at 10.1186/s12886-022-02516-6.

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Most cited references 34

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Visual outcome, optical quality, and patient satisfaction with a new monofocal IOL, enhanced for intermediate vision: preliminary results

Rita Mencucci, Michela Cennamo, Daniel Venturi … (2020)

To compare visual outcomes, contrast sensitivity, optical quality, spectacle independence, and visual disturbances in patients implanted with 2 models of monofocal intraocular lenses (IOLs).

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Is Open Access

Extended Depth-of-Field Intraocular Lenses: An Update

Piotr Kanclerz, Francesca Toto, Andrzej Grzybowski … (2020)

Abstract Extended depth-of-focus (EDOF) is a new intraocular lens (IOL) technology in the treatment of presbyopia. In contrast to multifocal (MF) IOLs, EDOF lenses create a single elongated focal point, rather than several foci, to enhance depth of focus. In this way, EDOF IOLs aim to reduce photic phenomena, glare, and halos, which have been reported in MF IOLs. A potential disadvantage is a decrease of retinal image quality if the amount of the aberrations is excessively increased. Frequently, EDOF IOLs are combined with MF optical designs; for this reason, EDOF IOLs are commonly a subject of confusion with optical multifocality concepts. The aim of this article is to clarify what an EDOF IOL is and to discuss the recently reported outcomes with these IOLs. We propose naming lenses that have combined optical designs as “hybrid IOLs.”

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Repeatability of measurements with a double-pass system.

Alain Saad, Marc Saab, Damien Gatinel (2010)

To evaluate the repeatability of measurements with a double-pass system. Rothschild Foundation, Paris, France. Eyes were separated into 2 control groups ( 40 years), a post-refractive surgery group, and a cataract group. Measurements were performed using the Optical Quality Analysis System. The main outcome measures were the objective scattering index (OSI), the cutoff frequency of the modulation transfer function (MTF), and the Strehl ratio. The repeatability limit was obtained from the individual standard deviations. Forty-two eyes were evaluated. The mean OSI value was 0.47 +/- 0.11 (SD) in the younger control group, 1.73 +/- 0.26 in the older control group, 1.34 +/- 0.16 in the post-refractive surgery group, and 6.15 +/- 0.50 in the cataract group. The mean cutoff MTF value was 39.44 +/- 3.93 cycles per degree (cpd), 26.07 +/- 3.89 cpd, 28.34 +/- 2.84 cpd, and 13.3 +/- 1.69 cpd, respectively, and the mean Strehl ratio, 0.234 +/- 0.023, 0.146 +/- 0.021, 0.169 +/- 0.023, and 0.098 +/- 0.010, respectively. The repeatability limit for the whole population was 0.841 (33.5%) for the OSI, 8.499 (31.1%) for the cutoff MTF, and 0.051 (31%) for the Strehl ratio. The repeatability limit was good and equivalent for the OSI, the MTF, and the Strehl ratio values. There was a wide interval between the normal and pathologic threshold for OSI measurements, indicating that the reliability of the double-pass device complies with the requirements for quantitative assessment of scattering. No author has a financial or proprietary interest in any material or method mentioned. Copyright 2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

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Author and article information

Contributors

Kyungmin Koh: kmkoh@kimeye.com

Journal

Journal ID (nlm-ta): BMC Ophthalmol

Journal ID (iso-abbrev): BMC Ophthalmol

Title: BMC Ophthalmology

Publisher: BioMed Central (London )

ISSN (Electronic): 1471-2415

Publication date (Electronic): 14 July 2022

Publication date PMC-release: 14 July 2022

Publication date Collection: 2022

Volume: 22

Electronic Location Identifier: 302

Affiliations

[1 ]GRID grid.490241.a, ISNI 0000 0004 0504 511X, Department of Ophthalmology, , Kim’s Eye Hospital, Konyang University College of Medicine, ; 136 Youngshinro, Youngdeungpo-gu, Seoul, 07301 Republic of Korea

[2 ]GRID grid.267370.7, ISNI 0000 0004 0533 4667, Department of Ophthalmology, Asan Medical Center, , University of Ulsan College of Medicine, ; Seoul, Republic of Korea

Article

Publisher ID: 2516

DOI: 10.1186/s12886-022-02516-6

PMC ID: 9284875

PubMed ID: 35836144

SO-VID: 46129462-c823-45fb-921f-b0fb4b90dafe

License:

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

History

Date received : 18 January 2022

Date accepted : 21 June 2022

Custom metadata

ScienceOpen disciplines: Ophthalmology & Optometry

Keywords: continuous range of vision,extended depth of focus,intermediate vision,intraocular lens,near vision

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ScienceOpen disciplines: Ophthalmology & Optometry

Keywords: continuous range of vision, extended depth of focus, intermediate vision, intraocular lens, near vision

Comparative analysis of a presbyopia-correcting intraocular lens that combines extended depth-of-focus and bifocal profiles with a standard monofocal intraocular lens

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Abstract

Background

Methods

Results

Conclusions

Supplementary Information

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Karger: Ophthalmology

Most cited references 34

Visual outcome, optical quality, and patient satisfaction with a new monofocal IOL, enhanced for intermediate vision: preliminary results

Extended Depth-of-Field Intraocular Lenses: An Update

Repeatability of measurements with a double-pass system.

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