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      Changing patterns of mortality during the COVID-19 pandemic: Population-based modelling to understand palliative care implications

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          Abstract

          Background:

          COVID-19 has directly and indirectly caused high mortality worldwide.

          Aim:

          To explore patterns of mortality during the COVID-19 pandemic and implications for palliative care, service planning and research.

          Design:

          Descriptive analysis and population-based modelling of routine data.

          Participants and setting:

          All deaths registered in England and Wales between 7 March and 15 May 2020. We described the following mortality categories by age, gender and place of death: (1) baseline deaths (deaths that would typically occur in a given period); (2) COVID-19 deaths and (3) additional deaths not directly attributed to COVID-19. We estimated the proportion of people who died from COVID-19 who might have been in their last year of life in the absence of the pandemic using simple modelling with explicit assumptions.

          Results:

          During the first 10 weeks of the pandemic, there were 101,614 baseline deaths, 41,105 COVID-19 deaths and 14,520 additional deaths. Deaths in care homes increased by 220%, while home and hospital deaths increased by 77% and 90%, respectively. Hospice deaths fell by 20%. Additional deaths were among older people (86% aged ⩾ 75 years), and most occurred in care homes (56%) and at home (43%). We estimate that 22% (13%–31%) of COVID-19 deaths occurred among people who might have been in their last year of life in the absence of the pandemic.

          Conclusion:

          The COVID-19 pandemic has led to a surge in palliative care needs. Health and social care systems must ensure availability of palliative care to support people with severe COVID-19, particularly in care homes.

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          Most cited references27

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          Covid-19: a remote assessment in primary care

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            Grief During the COVID-19 Pandemic: Considerations for Palliative Care Providers

            The COVID-19 pandemic is anticipated to continue spreading widely across the globe throughout 2020. To mitigate the devastating impact of COVID-19, social distancing and visitor restrictions in healthcare facilities have been widely implemented. Such policies and practices, along with the direct impact of the spread of COVID-19, complicate issues of grief that are relevant to medical providers. We describe the relationship of the COVID-19 pandemic to anticipatory grief, disenfranchised grief, and complicated grief for individuals, families, and their providers. Further, we provide discussion regarding countering this grief through communication, advance care planning, and self-care practices. We provide resources for healthcare providers, in addition to calling on palliative care providers to consider their own role as a resource to other specialties during this public health emergency.
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              How many people will need palliative care in 2040? Past trends, future projections and implications for services

              Background Current estimates suggest that approximately 75% of people approaching the end-of-life may benefit from palliative care. The growing numbers of older people and increasing prevalence of chronic illness in many countries mean that more people may benefit from palliative care in the future, but this has not been quantified. The present study aims to estimate future population palliative care need in two high-income countries. Methods We used mortality statistics for England and Wales from 2006 to 2014. Building on previous diagnosis-based approaches, we calculated age- and sex-specific proportions of deaths from defined chronic progressive illnesses to estimate the prevalence of palliative care need in the population. We calculated annual change over the 9-year period. Using explicit assumptions about change in disease prevalence over time, and official mortality forecasts, we modelled palliative care need up to 2040. We also undertook separate projections for dementia, cancer and organ failure. Results By 2040, annual deaths in England and Wales are projected to rise by 25.4% (from 501,424 in 2014 to 628,659). If age- and sex-specific proportions with palliative care needs remain the same as in 2014, the number of people requiring palliative care will grow by 25.0% (from 375,398 to 469,305 people/year). However, if the upward trend observed from 2006 to 2014 continues, the increase will be of 42.4% (161,842 more people/year, total 537,240). In addition, disease-specific projections show that dementia (increase from 59,199 to 219,409 deaths/year by 2040) and cancer (increase from 143,638 to 208,636 deaths by 2040) will be the main drivers of increased need. Conclusions If recent mortality trends continue, 160,000 more people in England and Wales will need palliative care by 2040. Healthcare systems must now start to adapt to the age-related growth in deaths from chronic illness, by focusing on integration and boosting of palliative care across health and social care disciplines. Countries with similar demographic and disease changes will likely experience comparable rises in need. Electronic supplementary material The online version of this article (doi:10.1186/s12916-017-0860-2) contains supplementary material, which is available to authorized users.
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                Author and article information

                Journal
                Palliat Med
                Palliat Med
                PMJ
                sppmj
                Palliative Medicine
                SAGE Publications (Sage UK: London, England )
                0269-2163
                1477-030X
                24 July 2020
                : 0269216320944810
                Affiliations
                [1 ]Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King’s College London, London, UK
                [2 ]Marie Curie Hospice, Edinburgh, UK
                [3 ]Usher Institute, Old Medical School, The University of Edinburgh, Edinburgh, UK
                Author notes
                [*]Anna E Bone, Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King’s College London, Cicely Saunders Institute, Bessemer Road, London SE5 9PJ, UK. Email: anna.bone@ 123456kcl.ac.uk
                [*]

                equal contributors

                Author information
                https://orcid.org/0000-0002-8800-9581
                https://orcid.org/0000-0002-3056-059X
                https://orcid.org/0000-0002-9315-4871
                https://orcid.org/0000-0002-3687-1313
                https://orcid.org/0000-0002-9777-4373
                Article
                10.1177_0269216320944810
                10.1177/0269216320944810
                7385436
                32706299
                fbb89858-d901-4a48-a35e-0c5142b1ee0f
                © The Author(s) 2020

                This article is distributed under the terms of the Creative Commons Attribution 4.0 License ( https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page ( https://us.sagepub.com/en-us/nam/open-access-at-sage).

                History
                Funding
                Funded by: The Dunhill Medical Trust, ;
                Award ID: RPGF1906\177
                Categories
                Original Article
                Custom metadata
                corrected-proof
                ts1

                Anesthesiology & Pain management
                palliative medicine,pandemics,mortality,population health,nursing homes,health services

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