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      Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis.

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          Abstract

          Epidemiological and clinical evidence suggests that an increased intake of long-chain n-3 fatty acids protects against mortality from coronary artery disease. We aimed to test the hypothesis that long-term use of eicosapentaenoic acid (EPA) is effective for prevention of major coronary events in hypercholesterolaemic patients in Japan who consume a large amount of fish.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          1474-547X
          0140-6736
          Mar 31 2007
          : 369
          : 9567
          Affiliations
          [1 ] Kobe University, Kobe, Japan. yokoyama@med.kobe-u.ac.jp
          Article
          S0140-6736(07)60527-3
          10.1016/S0140-6736(07)60527-3
          17398308
          f95765af-04a2-4536-9a19-f5a0767ac6b3
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