Periprosthetic Joint Infection: Current Clinical Challenges

Nelson, Sandra B; Pinkney, Jodian A; Chen, Antonia F.; Tande, Aaron J.

doi:10.1093/cid/ciad360

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Periprosthetic Joint Infection: Current Clinical Challenges

Author(s): Sandra B Nelson , Jodian A Pinkney , Antonia F Chen , Aaron J Tande

Publication date Created: July 12 2023

Publication date (Electronic): July 12 2023

Journal: Clinical Infectious Diseases

Publisher: Oxford University Press (OUP)

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Abstract

Over the last several decades, periprosthetic joint infection has been increasing in incidence and is occurring in more complex patients. While there have been advances in both surgical and medical treatment strategies, there remain important gaps in our understanding. Here, we share our current approaches to the diagnosis and management of periprosthetic joint infection, focusing on frequent clinical challenges and collaborative interdisciplinary care.

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Most cited references 89

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Oral versus Intravenous Antibiotics for Bone and Joint Infection

Ho-Kwong Li, Ines Rombach, Rhea Zambellas … (2019)

The management of complex orthopedic infections usually includes a prolonged course of intravenous antibiotic agents. We investigated whether oral antibiotic therapy is noninferior to intravenous antibiotic therapy for this indication.