Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart.

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Abstract

Elderly patients are more sensitive than younger patients to myocardial ischemia, which results in higher mortality. We investigated how aging affects the cardioprotective AMP-activated protein kinase (AMPK) signaling pathway.

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Author and article information

Journal

Journal ID (iso-abbrev): Circulation

Title: Circulation

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Electronic): 1524-4539

ISSN (Print): 0009-7322

Publication date (Electronic): Jul 20 2010

Volume: 122

Issue: 3

Affiliations

[1 ] Department of Physiology, Fourth Military Medical University, Xi'an, China.

Article

Mid ID: NIHMS213448 Publisher Item ID: CIRCULATIONAHA.110.953208

DOI: 10.1161/CIRCULATIONAHA.110.953208

PMC ID: 2907453

PubMed ID: 20606117

SO-VID: eff3585d-9291-4d9e-9861-9b7b8cc3d5b8

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