Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Guidelines recommend administering antibiotics within 1 h of sepsis recognition but this recommendation remains untested by randomized trials. This trial was set up to investigate whether survival is improved by reducing the time before initiation of antimicrobial therapy by means of a multifaceted intervention in compliance with guideline recommendations.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Intensive Care Med

Title: Intensive care medicine

Publisher: Springer Nature

ISSN (Electronic): 1432-1238

ISSN (Print): 0342-4642

Publication date (Electronic): May 02 2017

Affiliations

[1 ] Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany.

[2 ] Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.

[3 ] Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.

[4 ] Service Prévention et Contrôle de l'Infection, Hôpitaux Universitaires de Genève, Geneva, Switzerland.

[5 ] Department of Anaesthesia and Intensive Care Medicine, Zentralklinik Bad Berka GmbH, Bad Berka, Germany.

[6 ] Department of Anesthesiology and Intensive Care Medicine, University Hospital Greifswald, Greifswald, Germany.

[7 ] Department of Surgery and the Li Ka Shing Knowledge Institute, St Michael's Hospital, University of Toronto, Ontario, Canada.

[8 ] Department of Anesthesiology and Intensive Care Medicine, University Hospital Leipzig, Leipzig, Germany.

[9 ] Division of Pulmonary and Critical Care Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USA.

[10 ] Department of Anesthesiology, University Hospital Ulm, Ulm, Germany.

[11 ] Department of Anesthesiology and Intensive Care Medicine, University Hospital Oldenburg, Oldenburg, Germany.

[12 ] Department of Anesthesiology, Surgical Intensive Care Medicine and Pain Therapy, Vivantes Hospital Neukölln, Berlin, Germany.

[13 ] Department of Intensive Care Medicine, University Hospital RWTH Aachen, Aachen, Germany.

[14 ] Department of Anesthesiology and Intensive Care Medicine, University Hospital Rostock, Rostock, Germany.

[15 ] Department of Anesthesiology, Intensive Care, Transfusion and Emergency Medicine and Pain Therapy, Bethel Hospital Bielefeld, Bielefeld, Germany.

[16 ] Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.

[17 ] Department of Anesthesiology and Intensive Care Medicine, Hospital of the Bundeswehr Berlin, Berlin, Germany.

[18 ] Department of Anesthesiology and Intensive Care Medicine, University Medical Center Kiel, Kiel, Germany.

[19 ] Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Helios Hospital Erfurt, Erfurt, Germany.

[20 ] Department of Anesthesiology and Intensive Care Medicine, University Hospital Tübingen, Tübingen, Germany.

[21 ] Department of Intensive Care Medicine, Helios Hospital Wuppertal, Wuppertal, Germany.

[22 ] University Hospital Ulm, Ulm, Germany.

[23 ] Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany. konrad.reinhart@med.uni-jena.de.

[24 ] Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany. konrad.reinhart@med.uni-jena.de.

Article

Publisher Item ID: 10.1007/s00134-017-4782-4

DOI: 10.1007/s00134-017-4782-4

PubMed ID: 28466151

SO-VID: ed22dde0-ec48-40b9-a62f-2120d022b11f

History

Keywords: Antimicrobial agents,Critical illness,Quality improvement,Septic shock/drug therapy

Data availability:

Keywords: Antimicrobial agents, Critical illness, Quality improvement, Septic shock/drug therapy

Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial.

Read this article at

Abstract

Related collections

The Physician

Author and article information

Journal

Affiliations

Article

History

Comments

Comment on this article

Similar content 101

Cited by 63