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      Third-Generation Autologous Chondrocyte Implantation (Cells Cultured Within Collagen Membrane) Is Superior to Microfracture for Focal Chondral Defects of the Knee Joint: Systematic Review and Meta-analysis.

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          Abstract

          To systematically review randomized controlled trials to compare clinical outcomes of microfracture (MFx) versus third-generation autologous chondrocyte implantation (ACI) for the treatment of focal chondral defects (FCDs) of the knee joint.

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          Author and article information

          Journal
          Arthroscopy
          Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
          Elsevier BV
          1526-3231
          0749-8063
          Aug 2022
          : 38
          : 8
          Affiliations
          [1 ] College of Osteopathic Medicine, Rocky Vista University, Parker, Colorado.
          [2 ] Department of Orthopaedic Surgery, St. Joseph's University Medical Center, Paterson, New Jersey.
          [3 ] Department of Orthopaedic Surgery, St. Joseph's University Medical Center, Paterson, New Jersey. Electronic address: matthewkraeutlermd@gmail.com.
          [4 ] University of Colorado School of Medicine, Aurora, Colorado.
          [5 ] Houston Methodist Hospital, Houston, Texas.
          [6 ] Department of Orthopaedic Surgery, St. Joseph's University Medical Center, Paterson, New Jersey; Academy Orthopaedics, Wayne, New Jersey, U.S.A.
          Article
          S0749-8063(22)00097-4
          10.1016/j.arthro.2022.02.011
          35283221
          e5f7a624-9150-4c66-808f-0decd7337a1f
          History

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