30
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Prolonged treatment execution time is a concern in CyberKnife robotic radiosurgery. Beam reduction and node reduction technique, and monitor unit optimization methods are adopted to reduce the treatment time. Usage of single collimator in the CyberKnife treatment plan can potentially reduce collimator exchange time. An optimal single collimator, which yields an acceptable dose distribution along with minimum number of nodes, beams, and monitor units, can be a versatile alternative for shortening treatment time. The aim of the present study is to find the optimal single collimator in CyberKnife treatment planning to shorten the treatment time with the acceptable dose distribution. A spherical planning target volume PTV1 was drawn in an anthropomorphic head and neck phantom. Plans with same treatment goals were generated for all the 12 collimators independently. D95% was selected as the prescribing isodose and the prescribed dose was 10 Gy. The plan of the optimal collimator size was evaluated for conformity, homogeneity, and dose spillage outside the target. The optimum collimator size and the target dimensions were correlated. The study was repeated with two other target volumes PTV2 and PTV3 for generalizing the results. Collimator sizes just above the diameter of the spherical PTVs were yielding least number of nodes and beams with acceptable dose distributions. The collimator size of 35 mm is optimum for the PTV1, whose diameter is 31.4 mm. Similarly, 50 mm collimator is optimum for PTV2 (diameter=45.2mm) and 20 mm collimator is optimum for PTV3 (Diameter=17.3 mm). The total number of monitor units is found to reduce with increasing collimator size. Optimal single collimator is found to be useful for shortening the treatment time in spherical targets. Studies on two clinical targets, (a brain metastasis and a liver metastasis cases) show comparable results with the phantom study.

          PACS numbers: 87.55.D, 87.55.de, 87.53.Ly, 87.55.kh, 87.56.nk, 87.55.ne, 87.55.‐x

          Related collections

          Most cited references12

          • Record: found
          • Abstract: found
          • Article: not found

          A simple scoring ratio to index the conformity of radiosurgical treatment plans. Technical note.

          I Paddick (2000)
          A conformity index is a measure of how well the volume of a radiosurgical dose distribution conforms to the size and shape of a target volume. Because the success of radiosurgery is related to the extremely conformal irradiation of the target, an accurate method for describing this parameter is important. Existing conformity ratios and indices used in radiosurgery are reviewed and criticized. It will be demonstrated that previously proposed measurements of conformity can, under certain conditions, give false perfect scores. A new conformity index is derived that gives an objective score of conformity for a treatment plan and gives no false scores. An analysis of five different treatment plans is made using both the existing scoring methods and the new conformity index.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            The CyberKnife Robotic Radiosurgery System in 2010.

            This review provides a complete technical description of the CyberKnife VSI System, the latest addition to the CyberKnife product family, which was released in September 2009. This review updates the previous technical reviews of the original system version published in the late 1990s. Technical developments over the last decade have impacted virtually every aspect of the CyberKnife System. These developments have increased the geometric accuracy of the system and have enhanced the dosimetric accuracy and quality of treatment, with advanced inverse treatment planning algorithms, rapid Monte Carlo dose calculation, and post-processing tools that allow trade-offs between treatment efficiency and dosimetric quality to be explored. This review provides a system overview with detailed descriptions of key subsystems. A detailed review of studies of geometric accuracy is also included, reporting a wide range of experiments involving phantom tests and patient data. Finally, the relationship between technical developments and the greatly increased range of clinical applications they have allowed is reviewed briefly.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Dose conformity of gamma knife radiosurgery and risk factors for complications.

              To quantitatively evaluate dose conformity achieved using Gamma Knife radiosurgery, compare results with those reported in the literature, and evaluate risk factors for complications. All lesions treated at our institution with Gamma Knife radiosurgery from May 1993 (when volume criteria were routinely recorded) through December 1998 were reviewed. Lesions were excluded from analysis for reasons listed below. Conformity index (the ratio of prescription volume to target volume) was calculated for all evaluable lesions and for lesions comparable to those reported in the literature on conformity of linac radiosurgery. Univariate Cox regression models were used to test for associations between treatment parameters and toxicity. Of 1612 targets treated in 874 patients, 274 were excluded, most commonly for unavailability of individual prescription volume data because two or more lesions were included within the same dose matrix (176 lesions), intentional partial coverage for staged treatment of large arteriovenous malformations (AVMs) (33 lesions), and missing target volume data (26 lesions). The median conformity indices were 1.67 for all 1338 evaluable lesions and 1.40-1.43 for lesions comparable to two linac radiosurgery series that reported conformity indices of 1.8 and 2.7, respectively. Among all 651 patients evaluable for complications, there were one Grade 5, eight Grade 4, and 27 Grade 3 complications. Increased risk of toxicity was associated with larger target volume, maximum lesion diameter, prescription volume, or volume of nontarget tissue within the prescription volume. Gamma Knife radiosurgery achieves much more conformal dose distributions than those reported for conventional linac radiosurgery and somewhat more conformal dose distributions than sophisticated linac radiosurgery techniques. Larger target, nontarget, or prescription volumes are associated with increased risk of toxicity.
                Bookmark

                Author and article information

                Contributors
                h.sudahar@gmail.com
                Journal
                J Appl Clin Med Phys
                J Appl Clin Med Phys
                10.1002/(ISSN)1526-9914
                ACM2
                Journal of Applied Clinical Medical Physics
                John Wiley and Sons Inc. (Hoboken )
                1526-9914
                September 2012
                06 September 2012
                : 13
                : 5 ( doiID: 10.1002/acm2.2012.13.issue-5 )
                : 33-45
                Affiliations
                [ 1 ] Department of Radiotherapy Apollo Specialty Hospital Chennai 600035 India
                [ 2 ] Department of Medical Physics Anna University Chennai 600025 India
                Author notes
                [*] [* ]Corresponding author: Sudahar Harikrishnaperumal, Department of Radiotherapy, Apollo Speciality Hospital, 320, Padma Complex, Mount Road, Chennai ‐600035, India; phone: 914424331741; fax: 914424363646; email: h.sudahar@ 123456gmail.com
                Article
                ACM20033
                10.1120/jacmp.v13i5.3864
                5718220
                22955653
                e4539a5c-f4e6-43dc-9a1a-30080c4dafbe
                © 2012 The Authors.

                This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 26 December 2011
                : 15 May 2012
                Page count
                Figures: 10, Tables: 5, References: 12, Pages: 13, Words: 4858
                Categories
                Radiation Oncology Physics
                Radiation Oncology Physics
                Custom metadata
                2.0
                acm20033
                September 2012
                Converter:WILEY_ML3GV2_TO_NLMPMC version:5.2.5 mode:remove_FC converted:17.11.2017

                cyberknife,treatment time,optimal single collimator,nodes,monitor units,beams

                Comments

                Comment on this article