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      Mean platelet volume and coronary artery disease: a systematic review and meta-analysis.

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          Abstract

          Platelets with high hemostatic activity play an important role in the pathophysiology of coronary artery disease(CAD) and mean platelet volume(MPV) has been proposed as an indicator of platelet reactivity. Thus, MPV may emerge as a potential marker of CAD risk. The aim of this study was to conduct a systematic review and meta-analysis comparing mean difference in MPV between patients with CAD and controls and pooling the odds ratio of CAD in those with high versus low MPV.

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          Author and article information

          Journal
          Int. J. Cardiol.
          International journal of cardiology
          1874-1754
          0167-5273
          Aug 20 2014
          : 175
          : 3
          Affiliations
          [1 ] Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Cardiology Unit, Department of Internal Medicine, Phramongkutklao Hospital, Bangkok, Thailand.
          [2 ] Cardiology Unit, Department of Internal Medicine, Phramongkutklao Hospital, Bangkok, Thailand; Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Electronic address: thunyarat.ano@mahidol.ac.th.
          [3 ] Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
          [4 ] Centre for Clincial Epidemiology and Biostatistics, School of Medicine and Public Health, Faculty of Health and Medicine, University of New Castle, NSW, Australia.
          Article
          S0167-5273(14)01095-X
          10.1016/j.ijcard.2014.06.028
          25017904
          df9af397-8ad6-4b11-8dbf-6c0092869b31
          Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
          History

          Coronary artery disease,Mean platelet volume,Meta-analysis,Systematic review

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