15
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Cerebellar abiotrophy in a family of Border Collie dogs.

      Veterinary Pathology
      Animals, Atrophy, pathology, veterinary, Cerebellar Diseases, genetics, Dog Diseases, Dogs, Fatal Outcome, Female, Neurons, Afferent, Purkinje Cells

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Cerebellar abiotrophies have a nonsex-linked, autosomal, recessively inherited basis in a number of species, and lesions typically reflect profound and progressive loss of Purkinje cells. In this report, an unusual form of abiotrophy is described for two sibling Border Collies. Extensive loss of the cerebellar granular cell layer was present with relative sparing of Purkinje cells of two female pups. The biochemical basis for this form of cerebellar abiotrophy is unknown, but the lack of disease in other siblings supports an autosomal recessive mode of inheritance.

          Related collections

          Author and article information

          Journal
          12450206
          10.1354/vp.39-6-736

          Chemistry
          Animals,Atrophy,pathology,veterinary,Cerebellar Diseases,genetics,Dog Diseases,Dogs,Fatal Outcome,Female,Neurons, Afferent,Purkinje Cells

          Comments

          Comment on this article

          scite_
          40
          1
          58
          0
          Smart Citations
          40
          1
          58
          0
          Citing PublicationsSupportingMentioningContrasting
          View Citations

          See how this article has been cited at scite.ai

          scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

          Similar content341

          Cited by11