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      Evaluation of an online case study-based course in translational science for a broad scientific audience: Impacts on students’ knowledge, attitudes, planned scientific activities, and career goals

      research-article
      , ,
      Journal of Clinical and Translational Science
      Cambridge University Press
      Translational research, translational science, education, training, workforce, curriculum

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          Abstract

          Purpose:

          There is a need for education activities in translational science (TS) that focus on teaching key principles, concepts, and approaches to effectively overcome common scientific and operational bottlenecks in the translational process. Delivering this content to the broad range of individuals interested in advancing translation will help to both expand and develop the TS workforce. Rigorous evaluations will build the evidence base for effective educational approaches for varied audiences.

          Methods:

          In 2020, the National Center for Advancing Translational Sciences offered an online case study-based course in TS for students across education and career stages. The course evaluation used baseline and endpoint student surveys to assess satisfaction with the course and impacts of participation on knowledge and attitudes relevant to TS and professional goals.

          Results:

          Of 112 students, 100 completed baseline and/or endpoint surveys, with 66 completing both. Most found the online format ( n = 59, 83%) and case study approach ( n = 62, 87%) moderately or very effective. There were statistically significant increases in TS knowledge ( P < .001) and positive attitudes about team science in translational research (TR) ( P < .001). Students reported the course increased their skills and knowledge in cross-disciplinary team science, the process of preclinical and clinical TR, and how their work fits into the translational spectrum, and increased their interest in scientific approaches used in the case study and careers in TS, TR, or team science.

          Conclusions:

          This online case study-based course effectively conveyed TS concepts to students from a range of backgrounds and enhanced their professional interests related to course content.

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          Most cited references14

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          The theory of planned behavior

          Icek Ajzen (1991)
          Organizational Behavior and Human Decision Processes, 50(2), 179-211
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            • Article: not found

            Targeting metastasis.

            Tumour metastasis, the movement of tumour cells from a primary site to progressively colonize distant organs, is a major contributor to the deaths of cancer patients. Therapeutic goals are the prevention of an initial metastasis in high-risk patients, shrinkage of established lesions and prevention of additional metastases in patients with limited disease. Instead of being autonomous, tumour cells engage in bidirectional interactions with metastatic microenvironments to alter antitumour immunity, the extracellular milieu, genomic stability, survival signalling, chemotherapeutic resistance and proliferative cycles. Can targeting of these interactions significantly improve patient outcomes? In this Review preclinical research, combination therapies and clinical trial designs are re-examined.
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              Evaluating Training Programs: The Four Levels

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                Author and article information

                Journal
                J Clin Transl Sci
                J Clin Transl Sci
                CTS
                Journal of Clinical and Translational Science
                Cambridge University Press (Cambridge, UK )
                2059-8661
                2022
                07 June 2022
                : 6
                : 1
                : e82
                Affiliations
                Education Branch; Office of Policy, Communications and Education; National Center for Advancing Translational Sciences; National Institutes of Health ; Bethesda, MD, USA
                Author notes
                Address for correspondence: A. L. Vogel, PhD MPH, National Center for Advancing Translational Sciences, 6701 Democracy Boulevard, Bethesda, MD 20892-4874, USA. Email: vogelal@ 123456mail.nih.gov
                Author information
                https://orcid.org/0000-0002-2411-0736
                https://orcid.org/0000-0003-3837-6225
                https://orcid.org/0000-0001-9729-3660
                Article
                S2059866122004150
                10.1017/cts.2022.415
                9305082
                35949657
                de3adbd3-b23a-46e2-b5ae-f52e6c417ebd
                © The Author(s) 2022

                This is a work of the US Government and is not subject to copyright protection within the United States. Published by Cambridge University Press on behalf of The Association for Clinical and Translational Science.

                This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence ( https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 21 January 2022
                : 28 April 2022
                : 01 June 2022
                Page count
                Figures: 1, Tables: 4, References: 17, Pages: 8
                Categories
                Research Article
                Education

                translational research,translational science,education,training,workforce,curriculum

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