For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
21
views
66
references
 Top references
cited by
143
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      399
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Potential toxicity of polystyrene microplastic particles

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Environmental pollution arising from plastic waste is a major global concern. Plastic macroparticles, microparticles, and nanoparticles have the potential to affect marine ecosystems and human health. It is generally accepted that microplastic particles are not harmful or at best minimal to human health. However direct contact with microplastic particles may have possible adverse effect in cellular level. Primary polystyrene (PS) particles were the focus of this study, and we investigated the potential impacts of these microplastics on human health at the cellular level. We determined that PS particles were potential immune stimulants that induced cytokine and chemokine production in a size-dependent and concentration-dependent manner.

          Related collections

          Most cited references66

          • Record: found
          • Abstract: not found
          • Article: not found

          Microplastics and Nanoplastics in Aquatic Environments: Aggregation, Deposition, and Enhanced Contaminant Transport

          Nathalie Tufenkji, Laura Hernandez, Jeffrey Farner Budarz … (2018)
          Article 0 comments Cited 591 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Uptake and Accumulation of Polystyrene Microplastics in Zebrafish (Danio rerio) and Toxic Effects in Liver.

            Yifeng Lu, Yan Yan Zhang, Yongfeng Deng … (2016)
            Microplastics have become emerging contaminants, causing widespread concern about their potential toxic effects. In this study, the uptake and tissue accumulation of polystyrene microplastics (PS-MPs) in zebrafish were detected, and the toxic effects in liver were investigated. The results showed that after 7 days of exposure, 5 μm diameter MPs accumulated in fish gills, liver, and gut, while 20 μm diameter MPs accumulated only in fish gills and gut. Histopathological analysis showed that both 5 μm and 70 nm PS-MPs caused inflammation and lipid accumulation in fish liver. PS-MPs also induced significantly increased activities of superoxide dismutase and catalase, indicating that oxidative stress was induced after treatment with MPs. In addition, metabolomic analysis suggested that exposure to MPs induced alterations of metabolic profiles in fish liver and disturbed the lipid and energy metabolism. These findings provide new insights into the toxic effects of MPs on fish.
            Article 0 comments Cited 525 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Microplastics in bivalves cultured for human consumption.

              Lisbeth Van Cauwenberghe, Colin R Janssen (2014)
              Microplastics are present throughout the marine environment and ingestion of these plastic particles (<1 mm) has been demonstrated in a laboratory setting for a wide array of marine organisms. Here, we investigate the presence of microplastics in two species of commercially grown bivalves: Mytilus edulis and Crassostrea gigas. Microplastics were recovered from the soft tissues of both species. At time of human consumption, M. edulis contains on average 0.36 ± 0.07 particles g(-1) (wet weight), while a plastic load of 0.47 ± 0.16 particles g(-1) ww was detected in C. gigas. As a result, the annual dietary exposure for European shellfish consumers can amount to 11,000 microplastics per year. The presence of marine microplastics in seafood could pose a threat to food safety, however, due to the complexity of estimating microplastic toxicity, estimations of the potential risks for human health posed by microplastics in food stuffs is not (yet) possible.
              Article 0 comments Cited 495 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Contributors
                Se Yong Jung:
                ORCID: http://orcid.org/0000-0003-1337-563X
                JUNG811111@yuhs.ac.kr
                Jonghoon Choi:
                ORCID: http://orcid.org/0000-0003-3554-7033
                nanomed@cau.ac.kr
                Jinkee Hong:
                ORCID: http://orcid.org/0000-0003-3243-8536
                jinkee.hong@yonsei.ac.kr
                Journal
                Journal ID (nlm-ta): Sci Rep
                Journal ID (iso-abbrev): Sci Rep
                Title: Scientific Reports
                Publisher: Nature Publishing Group UK (London )
                ISSN (Electronic): 2045-2322
                Publication date (Electronic): 30 April 2020
                Publication date PMC-release: 30 April 2020
                Publication date Collection: 2020
                Volume: 10
                Electronic Location Identifier: 7391
                Affiliations
                [1 ]ISNI 0000 0004 0470 5454, GRID grid.15444.30, Department of Chemical and Biomolecular Engineering, Yonsei University, ; 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722 Republic of Korea
                [2 ]ISNI 0000 0001 0789 9563, GRID grid.254224.7, School of Integrative Engineering, Chung-Ang University, ; 84, Heukseok-ro, Dongjak-gu, Seoul, 06974 Republic of Korea
                [3 ]ISNI 0000 0004 0470 5454, GRID grid.15444.30, Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, ; Seoul, 03722 Korea
                Author information
                http://orcid.org/0000-0003-1337-563X
                http://orcid.org/0000-0003-3554-7033
                http://orcid.org/0000-0003-3243-8536
                Article
                Publisher ID: 64464
                DOI: 10.1038/s41598-020-64464-9
                PMC ID: 7193629
                PubMed ID: 32355311
                SO-VID: dad5be7f-d1ef-49fb-8bd9-a21b830300c0
                Copyright © © The Author(s) 2020
                License:

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

                History
                Date received : 11 September 2019
                Date accepted : 16 April 2020
                Funding
                Funded by: FundRef https://doi.org/10.13039/501100003725, National Research Foundation of Korea (NRF);
                Award ID: NRF-2019R1A6A3A03034115
                Award ID: NRF-2017R1E1A1A01074343
                Award Recipient :
                Categories
                Subject: Article
                Custom metadata
                issue-copyright-statement © The Author(s) 2020

                ScienceOpen disciplines: Uncategorized
                Keywords: cell culture,environmental monitoring,supramolecular polymers
                Data availability:
                ScienceOpen disciplines: Uncategorized
                Keywords: cell culture, environmental monitoring, supramolecular polymers

                Comments

                Comment on this article

                scite_

                Similar content399

                See all similar

                Cited by140

                See all cited by

                Most referenced authors1,480

                See all reference authors