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      A Systematic Approach for Evaluating the Quality of Experimental Toxicological and Ecotoxicological Data

      , ,
      Regulatory Toxicology and Pharmacology
      Elsevier BV

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          Abstract

          The evaluation of the quality of data and their use in hazard and risk assessment as a systematic approach is described. Definitions are proposed for reliability, relevance, and adequacy of data. Reliability is differentiated into four categories. Criteria relating to international testing standards for categorizing reliability are developed. A systematic documentation of evaluating reliability especially for use in the IUCLID database is proposed. This approach is intended to harmonize data evaluation processes worldwide. It may help the expert in subsequent assessments and should increase the clarity of evaluation.

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          Author and article information

          Journal
          Regulatory Toxicology and Pharmacology
          Regulatory Toxicology and Pharmacology
          Elsevier BV
          02732300
          February 1997
          February 1997
          : 25
          : 1
          : 1-5
          Article
          10.1006/rtph.1996.1076
          9056496
          d73a4046-5376-4da4-93cc-cfa4e7b9fe15
          © 1997

          https://www.elsevier.com/tdm/userlicense/1.0/

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