Redox Experimental Medicine

About

Redox Experimental Medicine is an open-access, peer-reviewed journal, publishing redox research that advances our understanding of the effect of redox processes on human health and disease. The journal publishes basic and translational articles which have potential therapeutic relevance, as well as pre-clinical and clinical studies.

Scope

Aberration in redox processes has a profound impact on the normal physiology of humans, with an implication in many diseases. Redox Experimental Medicine will serve as an essential publication for the international scientific community to translate experimental knowledge to redox-based preventive and/or therapeutic interventions, with a view to advancing health.

Redox Experimental Medicine covers all main areas of human pathophysiology, with special but not limited focus on healthy ageing and age-related diseases, cancer, cardiac and circulatory diseases, inflammatory-driven chronic diseases, endocrine and metabolic diseases, pregnancy, perinatal and newborn pathology, neurodegeneration, and infectious diseases. Redox-related nutrition and pharmacology also fit into the scope of the journal.

Redox Experimental Medicine considers for publication all articles which are scientifically sound. We welcome the following article types: research papers (including clinical trials), reviews, brief communications, debates and commentaries. The journal also publishes occasional invited special issues. The journal accepts quality observational studies, following thorough review.

The journal is newly launched, and as such does not yet have an impact factor. We aim to achieve indexing in PubMed as soon as possible, after which point all published articles will be indexed retrospectively. We also aim to achieve indexing in Web of Science so that the journal receives an impact factor as soon as possible, but unlikely to be sooner than 4 years after launch.

The Editorial Board aims to provide rapid and constructive peer review and will aim to give you a first decision within three weeks. The journal operates single anonymous peer review.

Publication Model

Redox Experimental Medicine is a fully gold open-access journal. Articles are published under a Creative Commons Attribution (CC BY) licence. Articles are freely available to everyone to read and reuse immediately upon publication, provided the terms of the licence are met.

For more information, please see our Open Access page.

Publication Metrics

• Time to first decision: Redox Experimental Medicine aims to return a decision on a peer-reviewed article in less than a month
• Time to online publication: Accepted manuscripts are published online and are fully citable within 24 hours of acceptance.

Publication charges

Bioscientifica is sponsoring the Article Publication Charge until 31 December 2024; as such authors can publish completely free of charge*.

Colour charges: There are no colour charges when publishing in Redox Experimental Medicine.

*Bioscientifica reserves the right to withdraw this offer at any time

Article Types

Redox Experimental Medicine publishes the following types of article:

• Research Articles
• Reviews
• Brief Communications
• Commentaries
• Editorials
• Letters to the Editor

Editorial Board

EDITOR-IN-CHIEF

Giuseppe Poli, MD, PhD General Pathology, PhD Biochemistry, PhD Hon
Emeritus Professor of General Pathology, University of Torino at San Luigi Hospital, Italy
Professor Poli has a degree in Medicine and Surgery and PhD in General Pathology, Turin University; PhD in Biochemistry, Brunel University of West London; Doctor Universitatis (hon), University of Buenos Aires. He is a lifetime honorary member of the Society for Free Radical Research-Europe and the Oxygen Club of California. His research interest has consistently focused on the role of lipids and lipid oxidation products (in particular, 4-hydroxynonenal and related aldehydes, cholesterol oxidation products) in cell signaling and function, inflammation, oxidant and antioxidant reactions, all translationally applied to pathological aging, inappropriate nutrition, atherosclerosis, carcinogenesis, Alzheimer’s disease and gastrointestinal diseases.

ASSOCIATE EDITORS

Fiorella Biasi, PhD Biology, PhD Experimental Pathology and Medicine
General Pathology Associate Professor, Dept of Clinical and Biological Sciences, Medical School, University of Torino, Italy
Professor Biasi's research focuses on the involvement of lipid peroxidation products, cholesterol metabolism and its oxidized compounds in the pathogenesis of human intestinal inflammatory diseases and colorectal cancer. Current research is on the role of diet and dietary lipids in modulating redox-dependent inflammatory signals affecting gut barrier damage, and possible interventions with natural anti-inflammatory/antioxidants, polyphenols, to be translated into clinical practice. Zero-waste policy by recycling food industry waste products rich in polyphenols as food ingredients potentially beneficial for health is also an ongoing research interest.

Ken Itoh, MD, PhD
Hirosaki University of Graduate Medicine, Hirosaki, Japan
Professor of the Department of Stress Response Science and Head of Biomedical Research Center at Hirosaki University Graduate School of Medicine, Hirosaki. Professor Itoh’s major research focus is on the stress response mechanisms against oxidative and electrophilic stresses both at transcriptional and translation levels, prevention of degenerative diseases by phytochemicals, the roles of mitochondrial reactive oxygen species and mitochondrial retrograde signals on aging and age-related diseases.

Anne Nègre-Salvayre, PhD Pharmacy
Senior Researcher Emeritus, INSERM, Institut of Metabolic and Cardiovascular Diseases, France
Dr Anne Nègre-Salvayre graduated in Pharmacy and has a PhD in Pharmaceutical Sciences. She was Head of the Team for Lipid Peroxidation Signalling and Vascular Diseases at INSERM UMR1048 in Toulouse from 2006 to 2020. She is presently Senior Researcher emeritus at INSERM U1297, Toulouse. Dr Nègre-Salvayre has authored more than 200 PubMed-indexed publications and communications. She is expert or external referee for international academic and non-academic councils including INSERM, HCERES, FDG and MRC. She is a member of The New French Society for Atherosclerosis, the European Society for Free Radicals and the HNE Club. Dr Nègre-Salvayre is expert in the field of lipid and sphingolipid biochemistry, and lipid peroxidation in atherosclerosis and vascular diseases.

EDITORS

Francesco Bellanti, MD, PhD Medical, Clinical and Experimental Sciences
Associate Professor of Internal Medicine, Department of Medical and Surgical Sciences, University of Foggia, Italy
After getting his MD in 2005, he started his research activity in 2007 during his residency in Internal Medicine. He got a PhD in Medical, Clinical and Experimental Sciences in 2013, followed by a Visiting Fellowship at the Scottish Centre of Regenerative Medicine, University of Edinburgh (UK), and further Post-Doctoral Fellowships. His research focuses on the study of mitochondria metabolism, redox balance and redox signalling applied to liver metabolism and pathophysiology, cell senescence, and stem cell physiology.

Hüveyda Başağa, PhD
Sabancy University, Istanbul, Turkey
Hüveyda Başağa has a degree in pharmacy and completed her PhD at Brunel University, London. Upon returning to Turkey she taught and conducted research at the Middle East Technical University, Ankara, after which she became a professor at the Department of Molecular Biology and Genetics, Bosphorus University, Istanbul. She has taught graduate and undergraduate level courses on free radical chemistry, biochemistry and molecular biology. Hüveyda Başağa participated in founding Sabanci University and presently she is an Emeritus Professor at the Faculty of Engineering and Natural Sciences. Her research interest focuses on oxidative stress/antioxidants, signal transduction and gene expression mechanisms. She has carried out research projects funded by Nato, Unesco, Tubitak and the EU.

Irundika Dias, PhD
Aston University, Birmingham, UK
Dr Dias' research focuses on understanding cellular effects of oxidative stress and its relevance to health and disease. To understand the mechanisms, she uses a variety of in vitro model systems and molecular biology, lipidomic tools. She has published more than 50 peer-reviewed articles in the fields of oxidative stress, inflammation and immunity.

Pablo Evelson, PhD Biochemistry
School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina
Professor Evelson's research is focused on the role of oxidative stress and inflammation in the toxicological mechanisms triggered by air pollution. Of particular interest is the role of mitochondria and mitochondrial dysfunction in the pathophysiology of the adverse health effects observed after the exposure to airborne particulate matter.

Cesar G Fraga, PhD Chemistry
University of Buenos Aires, Argentina
Dr Fraga is Plenary Full Professor of Physical Chemistry at the Universidad de Buenos Aires, Argentina, and Associate with the Agricultural Experiment Station (AES) at the University of California, Davis, USA. His research focuses on the roles of plant bioactives as health protectors in terms of nutrition and pharmacology, and their effects on chronic and metabolic diseases. His interest is to decipher the biochemical pathways, mainly those involving oxidative stress, redox homeostasis, and antioxidant actions, that affect cardiovascular, renal and intestinal physiology.

Morana Jaganjac, PhD
Ruder Boskovic Institute, Croatia
Morana Jaganjac is a Senior Scientist at Ruder Boskovic Institute, Division of Molecular Medicine in the Laboratory for Oxidative stress where she leads Metabolomics Unit. Her research interests focus on understanding the relevance of metabolic alterations and impaired redox homeostasis in tumorigenesis and metabolic syndrome.

Valerio Leoni, MD, PhD Clinical Biochemistry
Associate Professor of Clinical Biochemistry, University of Milano Bicocca, Italy
Dr Leoni's main area of research is the application of mass spectrometry to diagnostic process. He is also interested in metabolomics, lipidomics and metabolic biomarkers in aging, neurodegenerative and degenerative diseases.

Yunsook Lim, PhD
Kyung Hee University, Korea
Professor of Food and Nutrition within College of Human Ecology. Her research is focused on the nutritional application for prevention and treatment of metabolic diseases such as obesity and diabetes. In particular, her research interests focus on multiorgan regulation of antioxidant and anti-inflammatory nutrients and food ingredients in obesity and diabetes and their complications including NAFLD, renal failure, sarcopenia, dementia, etc.

Gérard Lizard, DEng, PhD
Inserm / University of Burgundy, France
Gérard Lizard is an INSA-Lyon biochemist engineer, PhD in Molecular and Cellular Biology and PhD in Human Biology. He was recruited to INSERM in 1991 and from 2012 to 2023 has been director of the Biochemistry Laboratory 'Peroxisome, Inflammation and Lipid Metabolism' at the University of Burgundy. He was one of the first researchers to work on cell death by apoptosis in the field of atherosclerosis, which led him to demonstrate that certain oxidized derivatives of cholesterol (oxysterols) induce a mode of cell death by oxiapoptophagy characterized by oxidative stress, apoptosis and autophagy. Gérard Lizard has gradually oriented his research on aging and the pathophysiology of age-related diseases by focusing on the lipotoxicity of oxysterols and on their impact on organelles (mitochondria, peroxisome). To prevent the toxicity of certain oxysterols, Gérard Lizard is interested in compounds from the Mediterranean diet (polyphenols, fatty acids, oils), synthetic molecules and functionalized nanoparticles.

Cristina Mas-Bargues, PhD Pharmacy
University of Valencia, Spain
Cristina Mas-Bargues is an Assistant Professor of the Physiology Department at the University of Valencia. Early Career Researcher focused on aging, specifically on the role of oxidative stress on stem cell aging, and the role of extracellular vesicles on redox modulation. She has made two stays in foreign countries: at the University of California at Berkeley to study the role of sirtuins in neural stem cell aging; and at the Albert Einstein College of Medicine at New York to investigate the role of Bcl-xL on healthy aging and frailty prevention. Her research pathway has been awarded twice with the Young Investigator Award.

Elizabeth New, PhD Chemistry
University of Sydney, Australia
Elizabeth New is Professor of Chemistry at the University of Sydney. She studied at the University of Sydney and Durham University before postdoctoral work at UC Berkeley. Her research focusses on the development of small molecule fluorescent sensors for biological and environmental applications.

Noriko Noguchi, PhD Biochemistry, MsMedSci
Doshisha University, Kyoto, Japan
Professor Noriko Noguchi received her BSc and PhD in biology (1981) and medicine (1987), respectively, from Tsukuba University, Japan. After spending one year at National Institute of Standards and Technology in Maryland, USA, as a guest researcher, she joined the Faculty of Research Center for Advanced Science and Technology, University of Tokyo. She became Professor at Faculty of Life and Medical Science, Doshisha University in 2005. She received the Young investigator award from Society of Free Radical Research International (SFRRI) in 1994. Her research interests include mechanisms of oxidative stress-induced diseases, especially redox signaling by reactive oxygen species and antioxidants.

Patricia I Oteiza, PhD Biochemistry
Professor of Nutrition, University of California, Davis, USA
Dr Oteiza is a Professor and Vice Chair of the Department of Environmental Toxicology and a Professor at the Department of Nutrition at the University of California, Davis. Her research is centered on the relevance of bioactives and trace elements on human health, with emphasis on the regulation of redox homeostasiss in health and disease. One of her two areas of research addresses the relevance of trace element nutrition and toxicant exposure on early development. Her other topic of research is focused on characterizing the beneficial actions of flavonoids in the mitigation of the adverse consequences of unhealthy diets and obesity. In this context, she particularly investigates the importance of the effects of flavonoids at the gastrointestinal tract on diet- and obesity-induced diabetes, cancer and altered behaviour/cognition.

Nazareno Paolocci, MD, PhD
Associate Professor of Medicine, Johns Hopkins University School of Medicine, USA
Dr Nazareno Paolocci is an assistant professor of medicine at the Johns Hopkins University School of Medicine. His research focuses on cardiovascular disease. He pioneered research that led to an intravenous treatment for late-stage heart failure. Dr Paolocci earned his MD and PhD in neurobiology at the University of Perugia in Italy. He completed a residency in clinical pathology at the University of Perugia and a postdoctoral fellowship in cardiology at Johns Hopkins. Dr Paolocci joined the Johns Hopkins faculty in 2002.

M. Cristina Polidori, MD, Mphil
Department of Internal Medicine, University Hospital of Cologne, Germany
M. Cristina Polidori is Full Professor and Head of Ageing Clinical Research at the Department of Internal Medicine of the University Hospital of Cologne in Germany. She belongs to the Management Team of the newly established Ward for Ageing Medicine of the same Department. Dr. Polidori is specialized in Gerontology and Geriatrics and holds a Master in Philosophy, as well as a Professorship of Physiological Chemistry. Dr. Polidori is former Fellow of the Harvard University and of the EU Marie-Curie Program Quality of Life and Management of Living Resources and is since 2014 Honorary Fellow of the Royal College of Physicians of London for her studies on healthy centenarians. She has been awarded with several national and international prizes, participated to several EU-funded programs also as WP leader and is editor and author of over 160 most relevant books and publications in the field (h-index 47). Her interests concern real life- to translational aspects of the biopsychosocial model of frailty, intrinsic capacity, person-centered medicine and biological ageing.

Hanne Røberg-Larsen, PhD
Department of Chemistry, University of Oslo, Norway
Dr. Røberg-Larsen is an associate professor at the Department of Chemistry, University of Oslo, where she leads the Bioanalytical Chemistry group. Her main research interest is to develop new analytical chemistry technology to improve organoids and organ-on-a-chip technology. In particular, the use of organoids to study the effects of persistent organic pollutants on human health and in relation to metabolic diseases.

Yoshiro Saito, PhD
Laboratory of Molecular Biology and Metabolism, Tohoku University, Japan
Professor of Laboratory of Molecular Biology and Metabolism in Graduate School of Pharmaceutical Sciences. His research is focused on the physiological and pathophysiological meanings of oxidative stress, lipid peroxidation, electrophiles and the antioxidative system. Of particular interest is the biological role, metabolism, and regulation of selenium and selenoproteins. The function of selenium transporter 'selenoprotein P' and in particular the implications of its excess in several diseases including type 2 diabetes are an ongoing research interest.

Tatjana Simic, MD, PhD
Faculty of Medicine, University of Belgrade, Serbia
Professor Simic has a degree in Medicine and PhD in Biochemistry, University of Belgrade. She is a Full Professor, specialist in Clinical Biochemistry and member of the Serbian Academy of Sciences and Arts. Her research interest has focused on the role of polymorphisms in genes encoding antioxidant enzymes (in particular glutathione transferases) in susceptibitlity to genitourinary tumors, the redox biology of these tumors and their resistance to chemotherapy. She also studies the functional relevance of antioxidant genetic profile in redox pathogenesis and progression of non-malignant diseases, such as chronic renal failure and chronic heart failure.

James Thorne, PhD
School of Food Science and Nutrition, University of Leeds, United Kingdom
Dr. James L Thorne, an Associate Professor of Cancer, Nutrition, and Epigenetics at the University of Leeds, is interested in how, at the molecular level, nutrition and metabolism can alter cancer signalling pathays. His work aims to underpin and contribute to emerging dietary guidance for cancer patients to help improve response to therapy and prolong survival. Currently, Dr Thorne's research aims to idenitify how specific nutrients and cellular metabolic alterations can potentiate, or inhibit, chemotherapy drug efficacy. He is also interested in the potential of phytochemicals and nutraceuticals, naturally occurring compounds with potential health benefits, in cancer prevention and treatment. Dr. Thorne’s research encompasses the study of chemoresistance, a major challenge in cancer treatment where cancer cells become resistant to chemotherapy drugs. His work in this area seeks to understand the underlying mechanisms of chemoresistance and find ways to overcome it.

Giuseppe Valacchi, PhD Physiology, PhD Neurobiology
North Carolina State University, USA
Professor Valacchi's research interests are the effect of exogenous and endogenous sources of oxidative stress, and signal pathways involved in the cellular responses to these insults with special focus on epithelial wound healing.

Maximo Vento, MD, PhD Pediatrics
University & Polytechnic Hospital La Fe; Emeritus Researcher, Health Research Institute La Fe, Valencia, Spain
Professor Vento’s research interests include physiology of fetal to neonatal transition, the microbiome in extremely preterm infants, prenatal infectious disease, and analytical methodology. Professor Vento is Chairman of the European Board of Neonatology (2018–2023), a Member of the Executive Committee of the European Society for Paediatric Research (2018–2023) and Chairman of the Spanish Maternal, Neonatal and Developmental Network Red (2015–2022).

Huiyong Yin, PhD Chemistry
Department of Biomedical Sciences, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong, China
Dr Huiyong Yin is currently a full professor and principal investigator at City University of Hong Kong. He is interested in understanding redox regulation of fatty acid and glucose metabolism in metabolic diseases with high prevalence in Chinese populations including atherosclerosis, hepatocellular carcinoma (HCC), hyperuricemia and gout, using mass spectrometry-based metabolomics/lipidomics in combination with biochemical tools, cell and animal models, human samples and clinical studies. Dr Yin has published around 150 peer-reviewed publications with >13,000 citations and an H Index of 62 (Google Scholar, Dec. 2023).

Amira Zarrouk, PhD
Faculty of Medicine of Sousse, University of Monastir, Tunisia
Assistant Professor at the Department of Biochemistry at the University of Sousse, Tunisia. She is interested in investigating systemic and local factors altered in aging and age-related diseases such as AD, multiple sclerosis, and sarcopenia. Her research focuses on identifying dysfunctional pathways, with a particular focus on lipid metabolism, mitochondrial function, oxidative stress, and inflammation. Her research interests also include identifying synthetic and natural molecules able to counter the development of age-related diseases and facilitate their treatment.

Author guidelines

Ready to submit? Go straight to submission.

Bioscientifica is committed to providing our authors with the support and resources they need to successfully publish their papers.
Visit the Bioscientifica author resource centre for advice.

Overview

Before submitting

Manuscript formatting

Article types

• Research Articles
• Reviews
• Brief Communications
• Commentaries
• Editorials
• Letters to the Editor

Supplementary data

Editorial policies

Submitting an article

Authors can find all the information needed to prepare articles for submission to Redox Experimental Medicine on our Author Guidelines page.

Once an article is ready to submit, authors are advised to visit our How to Submit page.

Submissions are managed though the Redox Experimental Medicine ScholarOne Manuscripts site.

Publication charges

Redox Experimental Medicine has the following publication charges:

• Article Publication Charge: Bioscientifica is sponsoring the Article Publication Charge until 31 December 2024; as such authors can publish completely free of charge*.
• Colour charges: There are no colour charges when publishing in Redox Experimental Medicine.

*Bioscientifica reserves the right to withdraw this offer at any time.

Peer review

Articles published in Redox Experimental Medicine undergo peer review before acceptance. Key facts about the peer-review process are given below:

• identity transparency: single anonymized
• reviewer interacts with: editor
• review information published: none

If an article is not accepted for publication, we may offer the author the opportunity to transfer their submission to other suitable journals published by Bioscientifica.

More information about the peer-review process can be found on our Peer-review process page.

Ethics

Redox Experimental Medicine maintains the highest standards of publication and research ethics and is a member of the Committee for Publication Ethics (COPE).

Authors, Reviewers and Editors are expected to comply with Bioscientifica’s Ethical Policy.

Diversity, Equity and Inclusion

Redox Experimental Medicine recognises that there are biases and inequalities in the publishing system. We are committed to scrutinising our own processes and policies to prevent bias, reduce inequality and better represent and serve our diverse community of authors, reviewers, editors and readers.

Research data

Redox Experimental Medicine supports open data and strongly encourages authors to publicly release all data supporting the analysis and conclusions of primary research articles, on or before publication of the article.

All primary research articles published in Redox Experimental Medicine should include a Data Availability Statement.

More information is on our Research data page.

Indexing

Redox Experimental Medicine is now indexed in the Directory of Open Access Journals (DOAJ).

Applications will be made for indexing in the following once enough articles have been published, and/or the minimum acceptance criteria have been met:

• PubMed Central
• Emerging Sources Citation Index (ESCI; Web of Science)

Abstracting and indexing

Redox Experimental Medicine

Online ISSN: 2755-158X

New for 2023: Redox Experimental Medicine is now indexed in the Directory of Open Access Journals (DOAJ).

Published articles will be fully referenced and linked to a wide variety of discoverability services. We anticipate that Redox Experimental Medicine will be accepted for inclusion in PubMed Central as soon as enough articles have been published, at which point indexing will be applied to all published articles retrospectively.

Redox Experimental Medicine will apply for indexing in Web of Science's Emerging Sources Citation Index (ESCI) as soon as the minimum assessment criteria have been met. This is required to secure an Impact Factor. In addition, the journal will be submitted for indexing to the Science Citation Index Expanded (SCIE), amongst others.

Digital preservation

Articles published in Redox Experimental Medicine are archived in LOCKSS and Portico to ensure that these articles are preserved in the long term.