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      Systematic Review and Meta-analysis: The Role of Diet in the Development of Nonalcoholic Fatty Liver Disease

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          Abstract

          The association of nonalcoholic fatty liver disease (NAFLD) with dietary factors is well established but not thoroughly investigated. This systematic review and meta-analysis synthesizes available evidence regarding the effect of nutrition on the presence and severity of NAFLD.

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          Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.

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            Is Open Access

            ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

            Non-randomised studies of the effects of interventions are critical to many areas of healthcare evaluation, but their results may be biased. It is therefore important to understand and appraise their strengths and weaknesses. We developed ROBINS-I (“Risk Of Bias In Non-randomised Studies - of Interventions”), a new tool for evaluating risk of bias in estimates of the comparative effectiveness (harm or benefit) of interventions from studies that did not use randomisation to allocate units (individuals or clusters of individuals) to comparison groups. The tool will be particularly useful to those undertaking systematic reviews that include non-randomised studies.
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              Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts

              Observational cohort studies and a secondary prevention trial have shown inverse associations between adherence to the Mediterranean diet and cardiovascular risk.
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                Author and article information

                Contributors
                (View ORCID Profile)
                Journal
                Clinical Gastroenterology and Hepatology
                Clinical Gastroenterology and Hepatology
                Elsevier BV
                15423565
                November 2021
                November 2021
                Article
                10.1016/j.cgh.2021.11.026
                34838723
                d7069d13-7df8-4320-b15b-4e6d268e545b
                © 2021

                https://www.elsevier.com/tdm/userlicense/1.0/

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