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Linking the Cell Cycle to Histone Modifications: Dot1, G1/S, and Cycling K79me2
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Abstract
In a recent issue of Molecular Cell, Schulze et al. (2009) described distinct distributions
and regulation of Dot1-dependent methylation states at lysine 79 on histone H3 and
showed cell-cycle regulation of K79 dimethylation on genes expressed during the G1/S
phase.