Effect of human papillomavirus on patterns of distant metastatic failure in oropharyngeal squamous cell carcinoma treated with chemoradiotherapy.

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Abstract

Important differences exist in the pattern and timing of distant metastases between human papillomavirus-initiated (HPV+) and HPV- oropharyngeal squamous cell carcinoma (OPSCC). However, our understanding of the natural history of distant metastases in HPV+ OPSCC and its implications for surveillance is limited.

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Journal

Journal ID (iso-abbrev): JAMA Otolaryngol Head Neck Surg

Title: JAMA otolaryngology-- head & neck surgery

ISSN (Electronic): 2168-619X

ISSN (Print): 2168-6181

Publication date (Electronic): May 1 2015

Volume: 141

Issue: 5

Affiliations

[1 ] Head and Neck Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

[2 ] Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

[3 ] Department of Otolaryngology-Head and Neck Surgery, Rush University, Chicago, Illinois.

[4 ] Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

Article

Publisher Item ID: 2173811

DOI: 10.1001/jamaoto.2015.136

PubMed ID: 25742025

SO-VID: d3ddb979-afa7-4805-9829-c97a56aee926

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