ERS International Congress 2023: highlights from the Airway Diseases Assembly

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Abstract

In this review, early career and senior members of Assembly 5 (Airway Diseases, Asthma, COPD and Chronic Cough) present key recent findings pertinent to airway diseases that were presented during the European Respiratory Society International Congress 2023 in Milan, Italy, with a particular focus on asthma, COPD, chronic cough and bronchiectasis. During the congress, an increased number of symposia, workshops and abstract presentations were organised. In total, 739 abstracts were submitted for Assembly 5 and the majority of these were presented by early career members. These data highlight the increased interest in this group of respiratory diseases.

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Novel mechanisms of disease progression and exacerbations of airway diseases, together with superior disease models, can be used to develop disease management and novel therapies. The 2023 #ERSCongress saw several advancements in this regard. https://bit.ly/47sd2g7

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Most cited references 131

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Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD

David A. Lipson, Frank Barnhart, Noushin Brealey … (2018)

The benefits of triple therapy for chronic obstructive pulmonary disease (COPD) with an inhaled glucocorticoid, a long-acting muscarinic antagonist (LAMA), and a long-acting β2-agonist (LABA), as compared with dual therapy (either inhaled glucocorticoid-LABA or LAMA-LABA), are uncertain.

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European Respiratory Society guidelines for the management of adult bronchiectasis.

Robert Wilson, Alan Timothy, Marta Almagro … (2017)

Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent exacerbations in many patients. There have been no previous international guidelines.The European Respiratory Society guidelines for the management of adult bronchiectasis describe the appropriate investigation and treatment strategies determined by a systematic review of the literature.A multidisciplinary group representing respiratory medicine, microbiology, physiotherapy, thoracic surgery, primary care, methodology and patients considered the most relevant clinical questions (for both clinicians and patients) related to management of bronchiectasis. Nine key clinical questions were generated and a systematic review was conducted to identify published systematic reviews, randomised clinical trials and observational studies that answered these questions. We used the GRADE approach to define the quality of the evidence and the level of recommendations. The resulting guideline addresses the investigation of underlying causes of bronchiectasis, treatment of exacerbations, pathogen eradication, long term antibiotic treatment, anti-inflammatories, mucoactive drugs, bronchodilators, surgical treatment and respiratory physiotherapy.These recommendations can be used to benchmark quality of care for people with bronchiectasis across Europe and to improve outcomes.

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Author and article information

Journal

Journal ID (nlm-ta): ERJ Open Res

Journal ID (iso-abbrev): ERJ Open Res

Journal ID (publisher-id): ERJOR

Journal ID (hwp): erjor

Title: ERJ Open Research

Publisher: European Respiratory Society

ISSN (Electronic): 2312-0541

Publication date Collection: March 2024

Publication date (Electronic): 25 March 2024

Volume: 10

Issue: 2

Electronic Location Identifier: 00891-2023

Affiliations

[1 ]Respiratory Disease Unit, Department of Medical Sciences, Surgery, and Neurosciences, University of Siena, Siena, Italy

[2 ]Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK

[3 ]Karolinska Severe Asthma Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital Huddinge, Stockholm, Sweden

[4 ]Division of Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

[5 ]Franciscus Gasthuis and Vlietland Hospital, Rotterdam, The Netherlands

[6 ]Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands

[7 ]Maastricht Universitair Medisch Centrum+, Maastricht, The Netherlands

[8 ]Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy

[9 ]North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

[10 ]Faculty of Medicine, Pavol Jozef Safarik University, Kosice, Slovakia

[11 ]Department of Clinical and Biological Sciences, University of Turin, Turin, Italy

[12 ]Institute of Translational Pharmacology, National Research Council (IFT-CNR), Palermo, Italy

[13 ]Neumóloga en Fundación Neumológica Colombiana Bogotá, Bogotá, Colombia

[14 ]Respiratory Medicine, CHU Sart-Tilman B35, University of Liège, GIGA I3, Liège, Belgium

[15 ]National Heart and Lung Institute, Imperial College London, London, UK

[16 ]Department of Pneumology and Critical Care Medicine, Thoraxklinik at Heidelberg University Hospital, Translational Lung Research Center Heidelberg, German Center for Lung Research (DZL), Heidelberg, Germany

[17 ]Department of Biomedical Informatics, Center for Preventive Medicine and Digital Health, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany

[18 ]Department of Experimental Medical Science, Unit of Respiratory Immunopharmacology, Lund University, Lund, Sweden

[19 ]Medicines Evaluation Unit, Manchester University NHS Foundation Trust, Manchester, UK

Author notes

Corresponding author: Augusta Beech ( augusta.beech@ 123456manchester.ac.uk )

Author information

James Baker https://orcid.org/0000-0002-0301-2002

Apostolos Bossios https://orcid.org/0000-0002-0494-2690

Gert-Jan Braunstahl https://orcid.org/0000-0001-7671-3742

Francesco Lombardi https://orcid.org/0000-0003-2254-5119

Alexander G. Mathioudakis https://orcid.org/0000-0002-4675-9616

Fabio Luigi Massimo Ricciardolo https://orcid.org/0000-0003-1826-5018

Florence Schleich https://orcid.org/0000-0002-2678-1373

Frederik Trinkmann https://orcid.org/0000-0001-5877-877X

Augusta Beech https://orcid.org/0000-0002-2690-5364

Article

Publisher ID: 00891-2023

DOI: 10.1183/23120541.00891-2023

PMC ID: 10962455

PubMed ID: 38529346

SO-VID: d1ebacef-16b1-4870-be24-d2a2a579c8b4

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This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ 123456ersnet.org

ERS International Congress 2023: highlights from the Airway Diseases Assembly

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Most cited references 131

Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology.

Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD

European Respiratory Society guidelines for the management of adult bronchiectasis.

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