5
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Socioeconomic Inequalities in Type 2 Diabetes: Mediation Through Status Anxiety?

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Objectives: While status anxiety has received attention as a potential mechanism generating health inequalities, empirical evidence is still limited. Studies have been ecological and have largely focused on mental and not physical health outcomes.

          Methods: We conducted individual-level analyses to assess status anxiety (feelings of inferiority resulting from social comparisons) and resources (financial difficulties) as mediators of the relationship between socioeconomic status (SES) (education/occupation/employment status) and type 2 diabetes (T2D). We used cross-sectional data of 21,150 participants (aged 18–70 years) from the Amsterdam-based HELIUS study. We estimated associations using logistic regression models and estimated mediated proportions using natural effect modelling.

          Results: Odds of status anxiety were higher among participants with a low SES [e.g., OR = 2.66 (95% CI: 2.06–3.45) for elementary versus academic occupation]. Odds of T2D were 1.49 (95% CI: 1.12–1.97) times higher among participants experiencing status anxiety. Proportion of the SES–T2D relationship mediated was 3.2% (95% CI: 1.5%–7.0%) through status anxiety and 10.9% (95% CI: 6.6%–18.0%) through financial difficulties.

          Conclusion: Status anxiety and financial difficulties played small but consistent mediating roles. These individual-level analyses underline status anxiety’s importance and imply that status anxiety requires attention in efforts to reduce health inequalities.

          Related collections

          Most cited references51

          • Record: found
          • Abstract: found
          • Article: not found

          The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations.

          In this article, we attempt to distinguish between the properties of moderator and mediator variables at a number of levels. First, we seek to make theorists and researchers aware of the importance of not using the terms moderator and mediator interchangeably by carefully elaborating, both conceptually and strategically, the many ways in which moderators and mediators differ. We then go beyond this largely pedagogical function and delineate the conceptual and strategic implications of making use of such distinctions with regard to a wide range of phenomena, including control and stress, attitudes, and personality traits. We also provide a specific compendium of analytic procedures appropriate for making the most effective use of the moderator and mediator distinction, both separately and in terms of a broader causal system that includes both moderators and mediators.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Social Conditions As Fundamental Causes of Disease

              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Mediation Analysis: A Practitioner's Guide

              This article provides an overview of recent developments in mediation analysis, that is, analyses used to assess the relative magnitude of different pathways and mechanisms by which an exposure may affect an outcome. Traditional approaches to mediation in the biomedical and social sciences are described. Attention is given to the confounding assumptions required for a causal interpretation of direct and indirect effect estimates. Methods from the causal inference literature to conduct mediation in the presence of exposure-mediator interactions, binary outcomes, binary mediators, and case-control study designs are presented. Sensitivity analysis techniques for unmeasured confounding and measurement error are introduced. Discussion is given to extensions to time-to-event outcomes and multiple mediators. Further flexible modeling strategies arising from the precise counterfactual definitions of direct and indirect effects are also described. The focus throughout is on methodology that is easily implementable in practice across a broad range of potential applications.
                Bookmark

                Author and article information

                Contributors
                Journal
                Int J Public Health
                Int J Public Health
                Int J Public Health
                International Journal of Public Health
                Frontiers Media S.A.
                1661-8556
                1661-8564
                02 October 2023
                2023
                : 68
                : 1606069
                Affiliations
                [1] 1 Department of Public and Occupational Health , Amsterdam UMC Location University of Amsterdam , Amsterdam Public Health Research Institute , Amsterdam, Netherlands
                [2] 2 Department of Political and Social Sciences , European University Institute , Florence, Italy
                [3] 3 Department of Public Health , University of Copenhagen , Copenhagen, Denmark
                Author notes

                Edited by: Matthias Richter, Martin Luther University of Halle-Wittenberg, Germany

                *Correspondence: Loes Crielaard, l.crielaard@ 123456amsterdamumc.nl
                Article
                1606069
                10.3389/ijph.2023.1606069
                10577225
                37849688
                cbb7b8c9-43a5-4803-aa57-6430592e039e
                Copyright © 2023 Crielaard, Motazedi, Galenkamp, van de Werfhorst, Hulvej Rod, Kuipers, Nicolaou and Stronks.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 06 April 2023
                : 04 September 2023
                Funding
                Funded by: Hartstichting , doi 10.13039/501100002996;
                Award ID: 2010T084
                Funded by: ZonMw , doi 10.13039/501100001826;
                Award ID: 200500003 531003015
                Funded by: Seventh Framework Programme , doi 10.13039/501100004963;
                Award ID: 278901
                The HELIUS study is conducted by the Amsterdam University Medical Centers, location AMC, and the Public Health Service of Amsterdam. Both organizations provided core support for HELIUS. The HELIUS study is also funded by the Dutch Heart Foundation (project number 2010T084), the Netherlands Organization for Health Research and Development (ZonMw) (project number 200500003), the European Union (FP-7) (project number 278901), and the European Fund for the Integration of non-EU immigrants (EIF) (project number 2013EIF013). The study reported here was additionally supported by the Netherlands Organization for Health Research and Development (ZonMw) (project number 531003015).
                Categories
                Public Health Archive
                Original Article

                Public health
                mediation,socioeconomic status,type 2 diabetes,status anxiety,feelings of inferiority

                Comments

                Comment on this article