36
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Clinical aspects of palliative care in advanced Parkinson’s disease

      review-article
      1 , 1 , 2 ,
      BMC Palliative Care
      BioMed Central
      Clinical aspects, End-stage, Palliative care, Parkinson’s disease

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Parkinson's disease (PD) is one of the most common neurodegenerative disorders of the elderly population. Few therapeutic options are available for patients with PD requiring palliative care. Treatment of the early stages of PD is entirely different from later stages. During the later stages, the palliative care model is introduced to provide the patient with comfort and support. Early palliative care in PD requires minimization of dyskinesias and decreasing occurrence of motor and non-motor off times in an effort to maximize independent motor function. In the later stages, the focus of treatment shifts to treating the predominant non-motor symptoms and having a more supportive and palliative nature. The purpose of this review is to provide a summary of the palliative care management issues and palliative care management options of end-stage PD patients.

          Related collections

          Most cited references52

          • Record: found
          • Abstract: found
          • Article: not found

          A systematic review of prevalence studies of dementia in Parkinson's disease.

          Substantial variation in the prevalence of dementia in Parkinson's disease (PDD) has been reported. The aim of this study was to review systematically and critically previous studies of the prevalence of PDD using PubMed to search the literature. Studies focusing on PD and PDD, as well as those examining on the epidemiology of dementia subtypes, were included. Predefined inclusion and exclusion criteria were used and the quality of the studies included was rated. Articles were included if: (1) the proportion of PDD among patients with either PD or dementia was reported in an original study; (2) patients had been subjected to prospective clinical examination; and (3) strategies to include all subjects with either PD or dementia within the community or hospital clinics within a geographical area were employed. Twelve studies of the prevalence of PD or PDD (1,767 patients included) and 24 prevalence studies of dementia subtypes (4,711 patients included) met the inclusion criteria. In the PD/PDD studies, the proportion (mean and 95% confidence interval) with PDD in PD was 24.5% (17.4-31.5). There were significant methodological variations between studies and in the four studies that matched the quality criteria most closely, the rate of PDD was 31.1% (20.1-42.1). The prevalence of PDD was estimated as 0.5% in subjects 65 years or older. The percentage of PDD among those with dementia was 3.6% (3.1-4.1), with an estimated prevalence of PDD of 0.2% in subjects aged 65 years or older. Despite methodological variation, this systematic review suggests that 24 to 31% of PD patients have dementia, and that 3 to 4% of the dementia in the population would be due to PDD. The estimated prevalence of PDD in the general population aged 65 years and over is 0.2 to 0.5%. Copyright (c) 2005 Movement Disorder Society.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Reliability, validity, and clinical correlates of apathy in Parkinson's disease.

            The authors examined a consecutive series of 50 patients for the presence of apathy, depression, anxiety, and neuropsychological deficits using a neuropsychological battery that included a recently designed apathy scale. This scale was found to be reliable and valid in the diagnosis of apathy in patients with PD. Of patients in the study, 12% showed apathy as their primary psychiatric problem, and 30% were both apathetic and depressed. Patients with apathy (with or without depression), showed significantly more deficits in both tasks of verbal memory and time-dependent tasks. Results suggest that apathy is a frequent finding in PD, is significantly associated with specific cognitive impairments, and may have a different mechanism than depression.
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Palliative Care: the World Health Organization's global perspective.

                Bookmark

                Author and article information

                Journal
                BMC Palliat Care
                BMC Palliat Care
                BMC Palliative Care
                BioMed Central
                1472-684X
                2012
                25 October 2012
                : 11
                : 20
                Affiliations
                [1 ]Department of Neurobiology, Care Sciences and Society, Division of Clinical Geriatric, Huddinge Hospital, R94, Karolinska Institute, Stockholm, Sweden, SE–141 86
                [2 ]Iranian Research Center on Healthy Aging, Sabzevar University of Medical Sciences, Sabzevar, Iran
                Article
                1472-684X-11-20
                10.1186/1472-684X-11-20
                3528486
                23098090
                ca9d2cfc-ba5d-4d05-8a9f-e14da11d8937
                Copyright ©2012 Lokk and Delbari; licensee BioMed Central Ltd.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 30 January 2012
                : 27 August 2012
                Categories
                Review

                Anesthesiology & Pain management
                palliative care,end-stage,parkinson’s disease,clinical aspects

                Comments

                Comment on this article