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      Catheterization Techniques for Anomalous Aortic Origin of Coronary Arteries

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          ABSTRACT

          Anomalous aortic origin of a coronary artery (AAOCA) is a rare congenital anomaly with a large spectrum of anatomical variations. Selective engagement of an AAOCA can present challenges during cardiac catheterization. A comprehensive understanding of the characteristics of major AAOCA can effectively assist operators for selecting and maneuvering catheters. This review outlines the recommended catheter manipulations based on the site of ectopic coronary origin. Identifying the initial course (prepulmonic, subpulmonic, interarterial or retroaortic course) is crucial for classifying each AAOCA. Besides invasive coronary angiography, coronary computed tomography angiography is frequently utilized to enhance the diagnostic assessment. Cardiac catheterization enables the use of intracoronary imaging and physiologic tools for accurately assessing the significance of AAOCA identified as at risk, mainly the anomalies associated with an interarterial course. Intravascular ultrasound is recognized as the gold standard for analyzing AAOCA with interarterial course. Optical tomography coherence imaging can be interesting to evaluate the rare AAOCA with a subpulmonic course, which are associated with ischemic symptoms or myocardial ischemia. Invasive physiological indices using pressure wires can be employed, with the caveat that their threshold values remain uncertain. Decision‐making can be challenging for patients with AAOCA. Both non‐invasive and invasive imaging tools are essential to support the final choice.

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          Most cited references40

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          Sudden deaths in young competitive athletes: analysis of 1866 deaths in the United States, 1980-2006.

          Sudden deaths in young competitive athletes are highly visible events with substantial impact on the physician and lay communities. However, the magnitude of this public health issue has become a source of controversy. To estimate the absolute number of sudden deaths in US competitive athletes, we have assembled a large registry over a 27-year period using systematic identification and tracking strategies. A total of 1866 athletes who died suddenly (or survived cardiac arrest), 19+/-6 years of age, were identified throughout the United States from 1980 to 2006 in 38 diverse sports. Reports were less common during 1980 to 1993 (576 [31%]) than during 1994 to 2006 (1290 [69%], P<0.001) and increased at a rate of 6% per year. Sudden deaths were predominantly due to cardiovascular disease (1049 [56%]), but causes also included blunt trauma that caused structural damage (416 [22%]), commotio cordis (65 [3%]), and heat stroke (46 [2%]). Among the 1049 cardiovascular deaths, the highest number of events in a single year was 76 (2005 and 2006), with an average of 66 deaths per year (range 50 to 76) over the last 6 years; 29% occurred in blacks, 54% in high school students, and 82% with physical exertion during competition/training, whereas only 11% occurred in females (although this increased with time; P=0.023). The most common cardiovascular causes were hypertrophic cardiomyopathy (36%) and congenital coronary artery anomalies (17%). In this national registry, the absolute number of cardiovascular sudden deaths in young US athletes was somewhat higher than previous estimates but relatively low nevertheless, with a rate of <100 per year. These data are relevant to the current debate surrounding preparticipation screening programs with ECGs and also suggest the need for systematic and mandatory reporting of athlete sudden deaths to a national registry.
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            Coronary artery anomalies: an entity in search of an identity.

            Coronary artery anomalies (CAAs) are a diverse group of congenital disorders whose manifestations and pathophysiological mechanisms are highly variable. The subject of CAAs is undergoing profound evolutionary changes related to the definition, morphogenesis, clinical presentation, diagnostic workup, prognosis, and treatment of these anomalies. To understand the clinical impact of CAAs, the fundamental challenge is the firm establishment, for a particular type of CAA, of a mechanism capable of interference with the coronary artery's function, which is to provide adequate blood flow to the dependent myocardium. The present review focuses on anomalous origination of a coronary artery from the opposite sinus--the subgroup of CAAs that has the most potential for clinical repercussions, specifically sudden death in the young. For this subgroup, solid diagnostic screening protocols should be established, especially for athletes and other young individuals subjected to extreme exertion. Intravascular ultrasonography is the preferred means to evaluate the mechanisms responsible for ischemia in anomalous origination of a coronary artery from the opposite sinus and other potentially significant CAAs. Patients symptomatic of anomalous origination of a coronary artery from the opposite sinus may undergo medical treatment/observation, coronary angioplasty with stent deployment, or surgical repair. To be competent to advise CAA carriers, especially in the context of sporting or military activities, cardiologists should undergo specific training in these disorders. Only multicenter collaboration on protocols dedicated to CAAs can give rise to the large-scale studies needed to define the prognosis and optimal treatment of these disorders.
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              Anomalous Aortic Origin of a Coronary Artery From the Inappropriate Sinus of Valsalva

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                Author and article information

                Contributors
                pcaubry@yahoo.fr
                Journal
                Catheter Cardiovasc Interv
                Catheter Cardiovasc Interv
                10.1002/(ISSN)1522-726X
                CCD
                Catheterization and Cardiovascular Interventions
                John Wiley and Sons Inc. (Hoboken )
                1522-1946
                1522-726X
                05 January 2025
                01 March 2025
                : 105
                : 4 ( doiID: 10.1002/ccd.v105.4 )
                : 825-837
                Affiliations
                [ 1 ] Department of Cardiology Pôle Santé Oreliance Saran France
                [ 2 ] Department of Cardiology Assistance Publique‐Hôpitaux de Paris Hôpital Bichat Paris France
                [ 3 ] Department of Cardiology Hôpital Marie‐Lannelongue, Groupe Paris Saint‐Joseph Le Plessis‐Robinson France
                [ 4 ] Department of Cardiology Institut National de Chirurgie Cardiaque et de Cardiologie Interventionnelle Luxembourg Luxembourg
                [ 5 ] Pôle Cardiovasculaire Imagerie et Interventionnel, Clinique les Fontaines Melun France
                [ 6 ] Department of Cardiology Centre Hospitalier de Gonesse Gonesse France
                Author notes
                [*] [* ] Correspondence: Pierre Aubry ( pcaubry@ 123456yahoo.fr )

                Author information
                http://orcid.org/0000-0002-5628-1054
                Article
                CCD31391
                10.1002/ccd.31391
                11874055
                39757696
                c953746d-b86d-4904-b55c-ca8e02ce56c2
                © 2025 The Author(s). Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

                History
                : 13 December 2024
                : 11 September 2024
                : 22 December 2024
                Page count
                Figures: 16, Tables: 0, Pages: 13, Words: 6613
                Funding
                Funded by: This paper is dedicated to the memory of Dr. Paolo Angelini (1941−2023), a pioneering figure in the field of anomalous coronary arteries. His legacy continues to inspire and guide the efforts of clinicians and researchers worldwide, ensuring improved outcomes for patients with anomalous coronary arteries.
                Categories
                Education
                Education
                Custom metadata
                2.0
                March 1, 2025
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.5.4 mode:remove_FC converted:03.03.2025

                anomalous coronary artery,coronary computed tomography angiography,coronary pressure indices,intracoronary imaging,invasive coronary angiography

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