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ErmB determinants and Tn916-Like elements in clinical isolates of Clostridium difficile.

Author(s): Valentina Carucci, Paola Mastrantonio, Patrizia Spigaglia, Fabrizio Barbanti

Publication date: 2005-05-31

Journal: Antimicrobial Agents and Chemotherapy

Keywords: Anti-Bacterial Agents, pharmacology, Clostridium difficile, drug effects, genetics, isolation & purification, DNA Transposable Elements, Drug Resistance, Bacterial, Erythromycin, Humans, Methyltransferases, Microbial Sensitivity Tests, Tetracycline Resistance

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Abstract

Erythromycin and tetracycline resistance was analyzed in 37 Clostridium difficile clinical isolates. Strains of different clonal origins showed different erythromycin and tetracycline resistance determinants and different genetic arrangements of the elements. In strains of recent isolation, the presence of Tn916-like elements, never found before in C. difficile clinical isolates, has been demonstrated.

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PubMed ID:: 15917571

PMC ID:: 1140533

DOI:: 10.1128/AAC.49.6.2550-2553.2005

ScienceOpen disciplines: Chemistry

Keywords: Anti-Bacterial Agents,pharmacology,Clostridium difficile,drug effects,genetics,isolation & purification,DNA Transposable Elements,Drug Resistance, Bacterial,Erythromycin,Humans,Methyltransferases,Microbial Sensitivity Tests,Tetracycline Resistance

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ScienceOpen disciplines: Chemistry

ErmB determinants and Tn916-Like elements in clinical isolates of Clostridium difficile.

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