Atopic dermatitis: current treatment guidelines. Statement of the experts of the Dermatological Section, Polish Society of Allergology, and the Allergology Section, Polish Society of Dermatology

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Abstract

Atopic dermatitis (AD) is a condition frequently encountered in medical practices across the country. More than 60% of children with AD are at risk to develop allergic rhinitis or asthma (the atopic march). Patients with AD have a unique predisposition to colonization or infection by Staphylococcus aureus. Treatments for AD need to rapidly control symptoms of the disease, improve quality of life and prevent exacerbations. Given the chronic and relapsing nature of the disease, therapies need to encourage good compliance and be well tolerated.

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Most cited references 71

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Atopic dermatitis.

Donald Leung, Thomas Bieber (2003)

Atopic dermatitis is a highly pruritic chronic inflammatory skin disorder affecting 10-20% of children worldwide. Symptoms can persist or begin in adulthood. It is also the most common cause of occupational skin disease in adults. This disease results from an interaction between susceptibility genes, the host's environment, pharmacological abnormalities, skin barrier defects, and immunological factors. New management approaches have evolved from advances in our understanding of the pathobiology of this common skin disorder.

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Eczema prevalence in the United States: data from the 2003 National Survey of Children's Health.

Caroline W Koudelka, Amber Simpson, Joanna Shaw … (2010)

Using the 2003 National Survey of Children's Health sponsored by the federal Maternal and Child Health Bureau, we calculated prevalence estimates of eczema nationally and for each state among a nationally representative sample of 102,353 children 17 years of age and under. Our objective was to determine the national prevalence of eczema/atopic dermatitis in the US pediatric population and to further examine geographic and demographic associations previously reported in other countries. Overall, 10.7% of children were reported to have a diagnosis of eczema in the past 12 months. Prevalence ranged from 8.7 to 18.1% between states and districts, with the highest prevalence reported in many of the East Coast states, as well as in Nevada, Utah, and Idaho. After adjusting for confounders, metropolitan living was found to be a significant factor in predicting a higher disease prevalence with an odds ratio of 1.67 (95% confidence interval of 1.19-2.35, P=0.008). Black race (odds ratio 1.70, P=0.005) and education level in the household greater than high school (odds ratio 1.61, P=0.004) were also significantly associated with a higher prevalence of eczema. The wide range of prevalence suggests that social or environmental factors may influence disease expression.

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The burden of atopic dermatitis: impact on the patient, family, and society.

Christie L Carroll, Rajesh Balkrishnan, Steven R Feldman … (2015)

Atopic dermatitis is a common disease of increasing prevalence. Affected individuals must cope with a significant psychosocial burden, in addition to dealing with the medical aspects of the disease. Furthermore, because this is primarily a disease of childhood, family members, especially parents, are also affected by the condition. Individuals and family members are burdened with time-consuming treatment regimens for the disease, as well as dietary and household changes. The financial impact of atopic dermatitis on families can also be great. Moreover, the cost to society is significant, with estimates ranging from less than 100 dollars to more than 2000 dollars per patient per year. It is estimated that the direct cost of atopic dermatitis in the United States alone is almost 1 billion dollars per year. Reducing the onus of this disease must take into account the full breadth of its burden. Targeting parents and caregivers with education and psychosocial support can decrease family and personal burden, which in turn may decrease the cost of treating the condition because of better medical, psychosocial, and family outcomes.

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Author and article information

Journal

Journal ID (nlm-ta): Postepy Dermatol Alergol

Journal ID (iso-abbrev): Postepy Dermatol Alergol

Journal ID (publisher-id): PDIA

Title: Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii

Publisher: Termedia Publishing House

ISSN (Print): 1642-395X

ISSN (Electronic): 2299-0046

Publication date (Electronic): 12 August 2015

Publication date (Print): August 2015

Volume: 32

Issue: 4

Pages: 239-249

Affiliations

[1 ]Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland. Head of the Department: Prof. Roman Nowicki MD, PhD

[2 ]School of Medical Science of Bialystok, Bialystok, Poland. Head of the Department: Prof. Zbigniew Puchalski MD, PhD

[3 ]Department of Dermatology and Immunodermatology, Medical University of Warsaw, Warsaw, Poland. Head of the Department: Prof. Cezary Kowalewski MD, PhD

[4 ]Department of Infectious Diseases and Allergology, Military Medical Institute, Warsaw, Poland. Head of the Department: Prof. Jerzy Kruszewski MD, PhD

[5 ]Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland. Head of the Department: Prof. Jacek Szepietowski MD, PhD

[6 ]Great Poland Center of Allergology and Aesthetic Dermatology “Art Clinic”, Poznan, Poland. Head of the Center: Paweł Silny MD, PhD

[7 ]Department of Experimental Dermatology and Cosmetology, Jagiellonian University Medical College, Krakow, Poland. Head of the Department: Prof. Radosław Śpiewak MD, PhD

Author notes

Address for correspondence: Prof. Roman Nowicki MD, PhD, Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, 7 Debinki St, 80-211 Gdansk, Poland. phone: +48 58 349 25 90, +48 501 032 994, fax: +48 58 349 25 86. e-mail: rnowicki@ 123456gumed.edu.pl

Article

Publisher ID: 25596

DOI: 10.5114/pdia.2015.53319

PMC ID: 4565838

PubMed ID: 26366146

SO-VID: c75f7cff-5f67-4a46-8512-f1a7963d21c2

License:

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

History

Date received : 30 June 2015

Date revision received : 30 June 2015

Date accepted : 30 June 2015

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