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      Anterior intercostal artery perforator flap for immediate reconstruction following breast conservation surgery

      other
      , MD 1 , , , MD 2 , , MD 1 , , MD 1
      Microsurgery
      John Wiley & Sons, Inc.

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          Abstract

          Introduction

          Oncoplastic breast surgery following breast conservation surgery (BCS) utilizes aesthetic breast reduction techniques, and these reconstructions entail either volume displacement or volume replacement depending on the size and location of the excised tumor. The anterior Intercostal flap (AICAP) for immediate reconstruction after BCS is scarcely described in the literature. In this study, we present our experience with the Anterior Intercoastal Artery Perforator flap in 16 patients with small breast sizes.

          Patients and Methods

          Sixteen patients underwent lumpectomy followed by immediate reconstruction with Anterior ICAP flap between 2019 and 2021 at Hadassah University Hospital. Median age was 49 (range 28–67). Breast cup size, lumpectomy to breast size ration, defect measurements and location are provided. Flap design and flap in‐setting was planned and executed according to the size and location of the defect determined at the time of surgery. Surgical technique is described. Diagram of proposed reconstruction according to defect location is proposed.

          Results

          Flap dimensions clinically matched the defect size or were slightly larger due to anticipated shrinkage of tissue post radiation with mean of 5.4 × 3.9 × 3.75 cm (range of 2.5–13 × 2–13.2 × 0.8–4.5 cm). Complications, namely one seroma and one mild infection, were seen in two patients. Median follow up was 3 months after completion of radiation. All reconstructions were satisfactory by both surgeon and patient at last post‐operative follow‐up visit.

          Conclusion

          The anterior ICAP flap is an important addition to the armamentarium of immediate reconstruction options after BCS, particularly in patients smaller size breast sizes.

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          Most cited references13

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          Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer.

          We conducted 20 years of follow-up of women enrolled in a randomized trial to compare the efficacy of radical (Halsted) mastectomy with that of breast-conserving surgery. From 1973 to 1980, 701 women with breast cancers measuring no more than 2 cm in diameter were randomly assigned to undergo radical mastectomy (349 patients) or breast-conserving surgery (quadrantectomy) followed by radiotherapy to the ipsilateral mammary tissue (352 patients). After 1976, patients in both groups who had positive axillary nodes also received adjuvant chemotherapy with cyclophosphamide, methotrexate, and fluorouracil. Thirty women in the group that underwent breast-conserving therapy had a recurrence of tumor in the same breast, whereas eight women in the radical-mastectomy group had local recurrences (P<0.001). The crude cumulative incidence of these events was 8.8 percent and 2.3 percent, respectively, after 20 years. In contrast, there was no significant difference between the two groups in the rates of contralateral-breast carcinomas, distant metastases, or second primary cancers. After a median follow-up of 20 years, the rate of death from all causes was 41.7 percent in the group that underwent breast-conserving surgery and 41.2 percent in the radical-mastectomy group (P=1.0). The respective rates of death from breast cancer were 26.1 percent and 24.3 percent (P=0.8). The long-term survival rate among women who undergo breast-conserving surgery is the same as that among women who undergo radical mastectomy. Breast-conserving surgery is therefore the treatment of choice for women with relatively small breast cancers. Copyright 2002 Massachusetts Medical Society
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            • Article: not found

            Comparative study of surgical margins in oncoplastic surgery and quadrantectomy in breast cancer.

            Oncoplastic surgery for breast cancer is a novel concept that combines a plastic surgical procedure with breast-conserving treatment to improve the final cosmetic results. The aim of this study was to evaluate the oncological safety of oncoplastic procedures by studying the status of the surgical margins of the excised tumor specimen in comparison with standard quadrantectomies. Thirty consecutive breast cancer patients undergoing oncoplastic surgery (group 1) and 30 patients undergoing standard quadrantectomy (group 2) were prospectively studied with regard to the stage of breast cancer, the surgical procedures performed, the volume of breast tissue excised, and the histopathology of the tumor specimen, with specific details on surgical margins. Patients who underwent oncoplastic surgery (group 1) were younger (mean age, 48.73 years) than patients who had a classic quadrantectomy (group 2; mean age, 55.76 years; P = .022). The mean volume of the excised specimen in group 1 was 200.18 cm(3), compared with 117.55 cm(3) in group 2 (P = .016). Surgical margins were negative in 25 cases out of 30 in group 1 and 17 out of 30 in group 2 (P = .05). The average length of the surgical margin was 8.5 mm in group 1 and 6.5 mm in group 2, but the difference was not statistically significant (P = .074). Oncoplastic surgery adds to the oncological safety of breast-conserving treatment because a larger volume of breast tissue can be excised and a wider negative margin can be obtained. It is especially indicated for large tumors, for which standard breast-conserving treatment has a high probability of leaving positive margins.
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              The lateral intercostal artery perforators: anatomical study and clinical application in breast surgery.

              The lateral intercostal artery perforator flaps are based on intercostal perforators that arise from the costal groove. Cadaver dissections have been performed to improve the understanding of lateral intercostal perforator anatomy. The clinical applications of this study are demonstrated. The intercostal perforators were dissected in 24 fresh cadavers and evaluated in a field that extended between the third and the eighth intercostal spaces and between the latissimus dorsi and pectoralis major muscles. Their relationship with the anterior border of the latissimus dorsi muscle and the serratus anterior vessels was investigated. A mean value of 3.91 perforators per side was found. The majority of the intercostal perforators were found between the fifth and the eighth intercostal space level (88.4 percent). Mean distances of intercostal perforators to the anterior border of the latissimus dorsi muscle varied between 2.67 and 3.49 cm. The largest or "dominant" perforator was most frequently found in the sixth intercostal space (38.6 percent of cases) at an average of 2.5 to 3.5 cm from the anterior border of the latissimus dorsi muscle. In 10 of 47 sides (21 percent), vascular connections were found between the serratus anterior branch and the intercostal perforators. The connection was observed more frequently in the seventh and the sixth intercostal spaces, in 38 percent and 30 percent of cases, respectively. This vascular connection enables harvest of a serratus anterior artery perforator flap. Lateral intercostal artery perforator flaps can be used to address challenging defects over the breast without sacrificing the pedicle of the latissimus dorsi muscle.
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                Author and article information

                Contributors
                netaad@gmail.com
                Journal
                Microsurgery
                Microsurgery
                10.1002/(ISSN)1098-2752
                MICR
                Microsurgery
                John Wiley & Sons, Inc. (Hoboken, USA )
                0738-1085
                1098-2752
                21 March 2022
                January 2023
                : 43
                : 1 ( doiID: 10.1002/micr.v43.1 )
                : 20-26
                Affiliations
                [ 1 ] Department of Plastic and Reconstructive Surgery Hadassah University Medical Center Jerusalem Israel
                [ 2 ] Department of General Surgery Hadassah University Medical Center Jerusalem Israel
                Author notes
                [*] [* ] Correspondence

                Neta Adler, Department of Plastic and Reconstructive Surgery, Hadassah Medical Center, Hebrew University, POB 12000 Jerusalem il‐9112001, Israel.

                Email: netaad@ 123456gmail.com

                Author information
                https://orcid.org/0000-0002-1518-6851
                https://orcid.org/0000-0001-9193-9280
                Article
                MICR30884
                10.1002/micr.30884
                10078757
                35312091
                c3761861-8ec6-428f-a614-7b76d385a785
                © 2022 The Authors. Microsurgery published by Wiley Periodicals LLC.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

                History
                : 08 January 2022
                : 25 May 2021
                : 11 March 2022
                Page count
                Figures: 4, Tables: 1, Pages: 7, Words: 4431
                Categories
                Clinical Article
                Clinical Articles
                Custom metadata
                2.0
                January 2023
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.2.7 mode:remove_FC converted:06.04.2023

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